Pyrethroids are broad-spectrum insecticides that widely used in many countries, while
humans may be exposed to these toxins by drinking or eating pesticide-contaminated foods …

Abstract Human carboxylesterase 1 (CES1), primarily expressed in the liver and adipocytes,
is responsible for the hydrolysis of endogenous esters (such as cholesteryl esters and …

The purpose of this review is to examine uses of carboxylesterase activity in environmental
monitoring with a specific emphasis on pyrethroid insecticides. The chapter begins with an …

Phthalate esters (PAEs), accompanied by phthalate monoesters as hydrolysis metabolites in
humans, have been widely used as plasticizers and exhibited disruptive effects on the …

Several mouse carboxylesterase (CES) isozymes have been identified, but information
about their roles in drug metabolism is limited. In this study, we purified and characterized a …

Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase
superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2) …

Abstract Human carboxylesterase 2 (CES2A), one of the most abundant hydrolases
distributed in human small intestine and colon, play key roles in the hydrolysis of a wide …

Abstract Carboxylesterase 1 (CES1) is a primary human hepatic hydrolase involved in
hydrolytic biotransformation of numerous medications. Considerable interindividual …

Carboxylesterases (CESs) play major roles in catalyzing the hydrolysis of a wide range of
ester-and amide-containing compounds. CESs dominate both the biotransformation of …

Carboxylesterases (CE) are ubiquitous enzymes responsible for the detoxification of
xenobiotics, including numerous clinically used drugs. Therefore, the selective inhibition of …