Pulmonary surfactant in health and human lung diseases: state of the art

M Griese - European Respiratory Journal, 1999 - Eur Respiratory Soc
Pulmonary surfactant is a complex and highly surface active material composed of lipids and
proteins which is found in the fluid lining the alveolar surface of the lungs. Surfactant …

Pulmonary surfactant: functions, abnormalities and therapeutic options

I Frerking, A Günther, W Seeger, U Pison - Intensive care medicine, 2001 - Springer
The first successful clinical pilot studies of surfactant replacement were published about 20
years ago as a logical extension of experimental studies showing beneficial effects in pre …

Understanding the principle biophysics concepts of pulmonary surfactant in health and disease

C Autilio, J Pérez-Gil - Archives of Disease in Childhood-Fetal and …, 2019 - fn.bmj.com
Pulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate
structure of mammalian alveoli along with successive compression-expansion respiratory …

[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation

YY Zuo, RAW Veldhuizen, AW Neumann… - … et Biophysica Acta (BBA …, 2008 - Elsevier
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …

Lung surfactant in subacute pulmonary disease

G Devendra, RG Spragg - Respiratory research, 2002 - Springer
Pulmonary surfactant is a surface active material composed of both lipids and proteins that is
produced by alveolar type II pneumocytes. Abnormalities of surfactant in the immature lung …

The pulmonary surfactant system: biochemical and clinical aspects

L Creuwels, LMG Van Golde, HP Haagsman - Lung, 1997 - Springer
This article starts with a brief account of the history of research on pulmonary surfactant. We
will then discuss the morphological aspects and composition of the pulmonary surfactant …

Pulmonary surfactant

RJ King - Journal of applied physiology, 1982 - journals.physiology.org
Pulmonary surfactant reduces the surface tension of the alveolar air-liquid interface, thereby
providing mechanical stability and preventing alveolar atelectasis. More than 50% of …

Pulmonary surfactant

LG Dobbs - Annual review of medicine, 1989 - annualreviews.org
Pulmonary surfactant is a chemically heterogeneous material that provides a stable, low
surface tension within the lung, thereby preventing alveolar collapse at low transpulmonary …

[PDF][PDF] Host defence capacities of pulmonary surfactant: evidence for 'non‐surfactant'functions of the surfactant system

U Pison, M Max, A Neuendank… - European journal of …, 1994 - researchgate.net
To perform its function as the organ for gas exchange, the lung of the adult human interfaces
directly with its environment through a surface of approximately 150 m2. This extensive …

[图书][B] The biology of surfactant

BA Hills - 1988 - books.google.com
There has been much resurgence of interest in surfactant over the last decade. Great
advances are being made in developing sources and forms of exogenous surfactant to …