Quadruplexes are higher‐order structures formed by natural guanine‐rich nucleic acid
sequences. They may play a role in gene regulation and in telomere function. This article …

There are many structures that can be adopted by nucleic acids other than the Watson‐Crick
duplex. In particular, a noncanonical four‐stranded topology, called a G‐quadruplex, is of …

ABSTRACT G-quadruplexes are higher-order DNA and RNA structures formed from G-rich
sequences that are built around tetrads of hydrogen-bonded guanine bases. Potential …

All guanine-rich DNA and RNA molecules tend to fold into inter-and intra-molecular
structures called G-quadruplexes. The core of a G-quadruplex is composed of at least two …

There are many structures that can be adopted by nucleic acids other than the famous
Watson–Crick duplex form. This tutorial review describes the guanine rich G-quadruplex …

G-quadruplexes are noncanonical, four-stranded nucleic acid secondary structures formed
in sequences containing consecutive runs of guanines. These G-quadruplex structures have …

Self-association of guanosine at millimolar concentrations has been observed in solution
since the 19th century as characterized by the ready formation of polycrystalline gels. In the …

G-quadruplexes are formed from guanine-rich sequences of DNA and RNA. They consist of
stacks of square arrangements of guanines called G-quartets. Increasing evidence suggests …

Metal ions stabilize quadruplex nucleic acids by coordinating the O6 guanine atoms from G-
quartets. These quartets form the basic motif of quadruplex structures. This article …

Guanine rich DNA has been known for decades to form unusual structures, although their
biological relevance was little understood. Recent advances have demonstrated that …