Transcriptional Circuits Regulating Developmental Processes in Candida albicans

DL Rodriguez, MM Quail, AD Hernday… - Frontiers in Cellular and …, 2020 - frontiersin.org
Candida albicans is a commensal member of the human microbiota that colonizes multiple
niches in the body including the skin, oral cavity, and gastrointestinal and genitourinary …

A sticky situation: untangling the transcriptional network controlling biofilm development in Candida albicans

EP Fox, CJ Nobile - Transcription, 2012 - Taylor & Francis
Candida albicans is a commensal microorganism of the human microbiome; it is also the
most prevalent fungal pathogen of humans. Many infections caused by C. albicans are a …

Development and regulation of single- and multi-species Candida albicans biofilms

MB Lohse, M Gulati, AD Johnson… - Nature Reviews …, 2018 - nature.com
Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

Candida albicans Commensalism and Pathogenicity Are Intertwined Traits Directed by a Tightly Knit Transcriptional Regulatory Circuit

JC Pérez, CA Kumamoto, AD Johnson - PLoS biology, 2013 - journals.plos.org
Systemic, life-threatening infections in humans are often caused by bacterial or fungal
species that normally inhabit a different locale in our body, particularly mucosal surfaces. A …

Transcriptional control of hyphal morphogenesis in Candida albicans

S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …

On and Off: Epigenetic Regulation of C. albicans Morphological Switches

E Iracane, S Vega-Estévez, A Buscaino - Pathogens, 2021 - mdpi.com
The human fungal pathogen Candida albicans is a dimorphic opportunistic pathogen that
colonises most of the human population without creating any harm. However, this fungus …

A Phenotypic Profile of the Candida albicans Regulatory Network

OR Homann, J Dea, SM Noble, AD Johnson - PLoS genetics, 2009 - journals.plos.org
Candida albicans is a normal resident of the gastrointestinal tract and also the most
prevalent fungal pathogen of humans. It last shared a common ancestor with the model …

Regulatory mechanisms controlling morphology and pathogenesis in Candida albicans

D Kadosh - Current opinion in microbiology, 2019 - Elsevier
Highlights•There is a strong association between C. albicans morphology and virulence.•C.
albicans morphology control mechanisms may serve as important antifungal …

From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis

V Basso, C d'Enfert, S Znaidi… - Fungal Physiology and …, 2019 - Springer
Candida albicans is a commensal yeast of most healthy individuals, but also one of the most
prevalent human fungal pathogens. During adaptation to the mammalian host, C. albicans …

Overexpression approaches to advance understanding of Candida albicans

LS Rai, L van Wijlick, M Chauvel… - Molecular …, 2022 - Wiley Online Library
Candida albicans is an opportunistic fungal pathogen that is responsible for infections linked
to high mortality. Loss‐of‐function approaches, taking advantage of gene knockouts or …