(+)-Calanolide A (1) as a natural product was previously found as an inhibitor of HIV-1
reverse transcriptase. In our further investigation of its template, racemic 11-demethyl-12 …

Viral infections and associated diseases are responsible for a substantial number of
mortality and public health problems around the world. Each year, infectious diseases kill …

In vivo anti-HIV efficacy of (+)-calanolide A has been evaluated in a hollow fiber mouse
model. It was demonstrated that the compound was capable of suppressing virus replication …

Viral diseases, such as acquired immunodeficiency syndrome (AIDS), respiratory diseases,
and hepatitis, are the leading causes of death in humans worldwide, despite the tremendous …

The human immunodeficiency virus (HIV) is responsible for acquired immune deficiency
syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy …

The high number of citations of the previous review on anti-HIV compounds from plants
published in 1998 in Planta Medica indicates the importance of natural products research in …

Since the ancient times, natural products have served as a major source of drugs. About fifty
percent of today's pharmaceutical drugs are derived from natural origin. Interest in natural …

Chemotherapy for AIDS has progressed steadily in the past decade with the advent of five
HIV reverse transcriptase inhibitors, protease inhibitors, and combination of the two …

Eight new coumarin compounds (1-8) were isolated by anti-HIV bioassay-guided
fractionation of an extract of Calophyllum lanigerum. The structures of calanolide A (1), 12 …

Numerous plant‐derived compounds have been evaluated for inhibitory effects against HIV
replication, and some coumarins have been found to inhibit different stages in the HIV …