Recent studies on natural products as anti-HIV agents
M Jung, S Lee, H Kim - Current medicinal chemistry, 2000 - ingentaconnect.com
The discovery of medicinal agents capable of specifically inhibiting human
immunodeficiency virus (HIV) is urgently needed due to its globally widespread infection …
immunodeficiency virus (HIV) is urgently needed due to its globally widespread infection …
Antivirals of ethnomedicinal origin: structure-activity relationship and scope
D Chattopadhyay, TN Naik - Mini reviews in medicinal …, 2007 - ingentaconnect.com
Ethnomedicinal plants have been used as source of candidate drugs for almost all diseases,
but the number of compounds having antiviral activity is scarce. Irrespective of type of …
but the number of compounds having antiviral activity is scarce. Irrespective of type of …
A cutting‐edge view on the current state of antiviral drug development
E De Clercq - Medicinal research reviews, 2013 - Wiley Online Library
Prominent in the current stage of antiviral drug development are:(i) for human
immunodeficiency virus (HIV), the use of fixed‐dose combinations (FDCs), the most recent …
immunodeficiency virus (HIV), the use of fixed‐dose combinations (FDCs), the most recent …
[图书][B] Natural products as antiviral agents
CK Chu, HG Cutler - 1992 - Springer
During the past fifty years, thousands of natural products have been isolated from plants,
fungi, and bacteria. Apart from intense searches by pharmaceutical companies for …
fungi, and bacteria. Apart from intense searches by pharmaceutical companies for …
Phytochemicals as antiviral agents: recent updates
R Ghildiyal, V Prakash, VK Chaudhary, V Gupta… - Plant-derived bioactives …, 2020 - Springer
The epidemic of viral diseases is a global concern, mandating an urgent need of most
promising antivirals. Some of the viral diseases can be cured by approved antiviral drugs …
promising antivirals. Some of the viral diseases can be cured by approved antiviral drugs …
HIV inhibitory natural products. Part 7. The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum
Y Kashman, KR Gustafson, RW Fuller… - Journal of Medicinal …, 1992 - ACS Publications
Eight new coumarin compounds (1-8) were isolated by anti-HIV bioassay-guided
fractionation of an extract of Calophyllum lanigerum. The structures of calanolide A (1), 12 …
fractionation of an extract of Calophyllum lanigerum. The structures of calanolide A (1), 12 …
Structure− activity modifications of the HIV-1 Inhibitors (+)-Calanolide A and (−)-Calanolide B
DL Galinis, RW Fuller, TC McKee… - Journal of Medicinal …, 1996 - ACS Publications
The Δ7, 8 olefinic linkages within (+)-calanolide A (1) and (−)-calanolide B (2) were
catalytically reduced to determine impact on the anti-HIV activity of the parent compounds. In …
catalytically reduced to determine impact on the anti-HIV activity of the parent compounds. In …
Anti‐HIV‐1 constituents from Clausena excavata: Part II. carbazoles and a pyranocoumarin
B Kongkathip, N Kongkathip… - … Journal Devoted to …, 2005 - Wiley Online Library
Three carbazole derivatives, O‐methylmukonal (1), 3‐formyl‐2, 7‐dimethoxycarbazole (2)
and clauszoline J (3), and a pyranocoumarin, clausenidin (4), were isolated from the …
and clauszoline J (3), and a pyranocoumarin, clausenidin (4), were isolated from the …
Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships
Y Guo, A Ma, X Wang, C Yang, X Chen, G Li… - Frontiers in …, 2022 - frontiersin.org
Viruses spread rapidly and are well-adapted to changing environmental events. They can
infect the human body readily and trigger fatal diseases. A limited number of drugs are …
infect the human body readily and trigger fatal diseases. A limited number of drugs are …
Structure-activity-relationship and mechanistic insights for anti-HIV natural products
Acquired Immunodeficiency Syndrome (AIDS), which chiefly originatesfroma retrovirus
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …