Recent studies on natural products as anti-HIV agents

M Jung, S Lee, H Kim - Current medicinal chemistry, 2000 - ingentaconnect.com
The discovery of medicinal agents capable of specifically inhibiting human
immunodeficiency virus (HIV) is urgently needed due to its globally widespread infection …

Antivirals of ethnomedicinal origin: structure-activity relationship and scope

D Chattopadhyay, TN Naik - Mini reviews in medicinal …, 2007 - ingentaconnect.com
Ethnomedicinal plants have been used as source of candidate drugs for almost all diseases,
but the number of compounds having antiviral activity is scarce. Irrespective of type of …

A cutting‐edge view on the current state of antiviral drug development

E De Clercq - Medicinal research reviews, 2013 - Wiley Online Library
Prominent in the current stage of antiviral drug development are:(i) for human
immunodeficiency virus (HIV), the use of fixed‐dose combinations (FDCs), the most recent …

[图书][B] Natural products as antiviral agents

CK Chu, HG Cutler - 1992 - Springer
During the past fifty years, thousands of natural products have been isolated from plants,
fungi, and bacteria. Apart from intense searches by pharmaceutical companies for …

Phytochemicals as antiviral agents: recent updates

R Ghildiyal, V Prakash, VK Chaudhary, V Gupta… - Plant-derived bioactives …, 2020 - Springer
The epidemic of viral diseases is a global concern, mandating an urgent need of most
promising antivirals. Some of the viral diseases can be cured by approved antiviral drugs …

HIV inhibitory natural products. Part 7. The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum

Y Kashman, KR Gustafson, RW Fuller… - Journal of Medicinal …, 1992 - ACS Publications
Eight new coumarin compounds (1-8) were isolated by anti-HIV bioassay-guided
fractionation of an extract of Calophyllum lanigerum. The structures of calanolide A (1), 12 …

Structure− activity modifications of the HIV-1 Inhibitors (+)-Calanolide A and (−)-Calanolide B

DL Galinis, RW Fuller, TC McKee… - Journal of Medicinal …, 1996 - ACS Publications
The Δ7, 8 olefinic linkages within (+)-calanolide A (1) and (−)-calanolide B (2) were
catalytically reduced to determine impact on the anti-HIV activity of the parent compounds. In …

Anti‐HIV‐1 constituents from Clausena excavata: Part II. carbazoles and a pyranocoumarin

B Kongkathip, N Kongkathip… - … Journal Devoted to …, 2005 - Wiley Online Library
Three carbazole derivatives, O‐methylmukonal (1), 3‐formyl‐2, 7‐dimethoxycarbazole (2)
and clauszoline J (3), and a pyranocoumarin, clausenidin (4), were isolated from the …

Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships

Y Guo, A Ma, X Wang, C Yang, X Chen, G Li… - Frontiers in …, 2022 - frontiersin.org
Viruses spread rapidly and are well-adapted to changing environmental events. They can
infect the human body readily and trigger fatal diseases. A limited number of drugs are …

Structure-activity-relationship and mechanistic insights for anti-HIV natural products

R Kaur, P Sharma, GK Gupta, F Ntie-Kang, D Kumar - Molecules, 2020 - mdpi.com
Acquired Immunodeficiency Syndrome (AIDS), which chiefly originatesfroma retrovirus
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …