Canonical functions of mitochondria include the regulation of cellular survival, orchestration
of anabolic and metabolic pathways, as well as reactive oxygen species (ROS) signaling …

A growing literature indicates that mitochondria are key participants in innate immune
pathways, functioning as both signaling platforms and contributing to effector responses. In …

Mitochondria are versatile organelles and essential components of numerous biological
processes such as energy metabolism, signal transduction, and cell fate determination. In …

Inflammation is a cellular and molecular response to infection and/or tissues injury. While a
suited inflammatory response in intensity and time allows for killing pathogens, clearing …

The innate immune system has a key role in the mammalian immune response. Recent
research has demonstrated that mitochondria participate in a broad range of innate immune …

Inflammation represents a comprehensive host response to external stimuli for the purpose
of eliminating the offending agent, minimizing injury to host tissues and fostering repair of …

Mitochondrial dysfunction is associated with the manifestation and origin of a plethora of
diseases and disorders. Whilst classically the role of these archetypical 'powerhouses' in …

Mitochondria, the dynamic organelles and power house of eukaryotic cells function as
metabolic hubs of cells undergoing continuous cycles of fusion and fission. Recent findings …

The main features that are commonly attributed to mitochondria consist of the regulation of
cell proliferation, ATP generation, cell death and metabolism. However, recent scientific …

Mitochondria are key organelles involved in energy production, functioning as the metabolic
hubs of cells. Recent findings emphasize the emerging role of the mitochondrion as a key …