Mitochondrial metabolism regulates macrophage biology
Y Wang, N Li, X Zhang, T Horng - Journal of Biological Chemistry, 2021 - ASBMB
Mitochondria are critical for regulation of the activation, differentiation, and survival of
macrophages and other immune cells. In response to various extracellular signals, such as …
macrophages and other immune cells. In response to various extracellular signals, such as …
Innate immunity and tolerance toward mitochondria
A Rongvaux - Mitochondrion, 2018 - Elsevier
Mitochondria are intracellular organelles that originate from a bacterial symbiont, and they
retain multiple features of this bacterial ancestry. The immune system evolved to detect the …
retain multiple features of this bacterial ancestry. The immune system evolved to detect the …
Alterations in mitochondrial morphology as a key driver of immunity and host defence
MP Cervantes‐Silva, SL Cox, AM Curtis - EMBO reports, 2021 - embopress.org
Mitochondria are dynamic organelles whose architecture changes depending on the cell's
energy requirements and other signalling events. These structural changes are collectively …
energy requirements and other signalling events. These structural changes are collectively …
The role of mitophagy in innate immune responses triggered by mitochondrial stress
Y Song, Y Zhou, X Zhou - Cell Communication and signaling, 2020 - Springer
Mitochondria are important cellular organelles involved in many different functions, from
energy generation and fatty acid oxidation to cell death regulation and immune responses …
energy generation and fatty acid oxidation to cell death regulation and immune responses …
[HTML][HTML] Mitochondria as a centrally positioned hub in the innate immune response
Mitochondria are vital organelles involved in numerous cellular functions ranging from
energy metabolism to cell survival. Emerging evidence suggests that mitochondria provide a …
energy metabolism to cell survival. Emerging evidence suggests that mitochondria provide a …
Powering the immune system: mitochondria in immune function and deficiency
Mitochondria are critical subcellular organelles that are required for several metabolic
processes, including oxidative phosphorylation, as well as signaling and tissue‐specific …
processes, including oxidative phosphorylation, as well as signaling and tissue‐specific …
Basic mechanism of immune system activation by mitochondria
Y Iwasaki, Y Takeshima, K Fujio - Immunological medicine, 2020 - Taylor & Francis
Almost 160 years after the discovery of mitochondria, they are known for their production of
energy and are called “the powerhouse of the cell”. Recently, immune-metabolism has been …
energy and are called “the powerhouse of the cell”. Recently, immune-metabolism has been …
Mitochondrial damage-associated molecular patterns: from inflammatory signaling to human diseases
S Grazioli, J Pugin - Frontiers in immunology, 2018 - frontiersin.org
Over the recent years, much has been unraveled about the pro-inflammatory properties of
various mitochondrial molecules once they are leaving the mitochondrial compartment. On …
various mitochondrial molecules once they are leaving the mitochondrial compartment. On …
Mitochondrial control of inflammation
Numerous mitochondrial constituents and metabolic products can function as damage-
associated molecular patterns (DAMPs) and promote inflammation when released into the …
associated molecular patterns (DAMPs) and promote inflammation when released into the …
Unraveling the link between mitochondrial dynamics and neuroinflammation
LG de Oliveira, YS Angelo, AH Iglesias… - Frontiers in …, 2021 - frontiersin.org
Neuroinflammatory and neurodegenerative diseases are a major public health problem
worldwide, especially with the increase of life-expectancy observed during the last decades …
worldwide, especially with the increase of life-expectancy observed during the last decades …