Micro/nanofluidic-electrochemical biosensors for in situ tumor cell analysis

J Han, S Liu, Z Wang, Y Wu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Micro/nanofluidics have been demonstrated as exciting avenues for efficient capture and in
situ analysis of tumor cells, which is of great importance for early tumor diagnosis, staging …

Application and outlook of electrochemical technology in single-cell analysis

K Huang, YH Wang, H Zhang, TY Wang, XH Liu… - Biosensors and …, 2023 - Elsevier
Cellular heterogeneity, especially in some important diseased cells like tumor cells, acts as
an invisible driver for disease development like cancer progression in the tumor ecosystem …

Microfabricated Electrochemical Cell-Based Biosensors for Analysis of Living Cells In Vitro

J Wang, C Wu, N Hu, J Zhou, L Du, P Wang - Biosensors, 2012 - mdpi.com
Cellular biochemical parameters can be used to reveal the physiological and functional
information of various cells. Due to demonstrated high accuracy and non-invasiveness …

Current research status of tumor cell biomarker detection

L Jiang, X Lin, F Chen, X Qin, Y Yan, L Ren… - Microsystems & …, 2023 - nature.com
With the annual increases in the morbidity and mortality rates of tumors, the use of
biomarkers for early diagnosis and real-time monitoring of tumor cells is of great importance …

A review of innovative electrochemical strategies for bioactive molecule detection and cell imaging: Current advances and challenges

H Zhang, H Jiang, X Liu, X Wang - Analytica Chimica Acta, 2024 - Elsevier
Cellular heterogeneity poses a major challenge for tumor theranostics, requiring high-
resolution intercellular bioanalysis strategies. Over the past decades, the advantages of …

Integrated multifunctional electrochemistry microchip for highly efficient capture, release, lysis, and analysis of circulating tumor cells

S Yan, P Chen, X Zeng, X Zhang, Y Li, Y Xia… - Analytical …, 2017 - ACS Publications
The circulating tumor cells (CTCs) in the blood allow the noninvasive analysis of metastatic
mechanisms, cancer diagnosis, prognosis, disease monitoring, and precise therapy through …

Cancer cell analyses at the single cell-level using electroactive microwell array device

M Kobayashi, SH Kim, H Nakamura, S Kaneda, T Fujii - PloS one, 2015 - journals.plos.org
Circulating tumor cells (CTCs), shed from primary tumors and disseminated into peripheral
blood, are playing a major role in metastasis. Even after isolation of CTCs from blood, the …

Shifting paradigm of cancer diagnoses in clinically relevant samples based on miniaturized electrochemical nanobiosensors and microfluidic devices

K Mahato, A Kumar, PK Maurya, P Chandra - Biosensors and Bioelectronics, 2018 - Elsevier
Cancer is one of leading causes of death in the world and occurs in more than two hundred
types according to the National Cancer Institute. Its early diagnosis has been remained a …

Integrating electrochemical immunosensing and cell adhesion technologies for cancer cell detection and enumeration

R Seenivasan, JW Warrick, CI Rodriguez, W Mattison… - Electrochimica …, 2018 - Elsevier
We have successfully integrated techniques for controlling cell adhesion and performing
electrochemical differential pulse voltammetry (DPV) through the use of digitally controlled …

Electrochemical biosensors for stem cell analysis; applications in diagnostics, differentiation and follow-up

H Nasrollahpour, B Khalilzadeh, A Naseri… - TrAC Trends in …, 2022 - Elsevier
Sophisticated and well-designed tools with the capability of monitoring cellular mechanisms
and dynamics are integral to monitoring pathological conditions and anaplastic changes. To …