Prostate cancer is the most common cancer in men in Europe and the United States. The
genetic heritability of prostate cancer is contributed to by both rarely occurring genetic …

Worldwide, familial and epidemiological studies have generated considerable evidence of
an inherited component to prostate cancer. Indeed, rare highly penetrant genetic mutations …

Background: Several prostate cancer genome-wide association studies (GWAS) have
identified risk-associated genetic variants primarily in populations of European descent …

Genome-wide association studies (GWAS) have been successful in deciphering the genetic
component of predisposition to many human complex diseases including prostate cancer …

Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify …

Genome-wide association studies (GWAS) have identified multiple common genetic variants
associated with an increased risk of prostate cancer (PrCa), but these explain less than one …

Prostate cancer (PrCa) is the most common non-skin cancer diagnosed among males in
developed countries and the second leading cause of cancer mortality, yet little is known …

Abstract Background: Of the 200,000 US men annually diagnosed with prostate cancer,
approximately 20% to 30% will have clinically aggressive disease. Although factors such as …

Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …

The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …