The chondroitin sulfate proteoglycans (CSPGs) have been implicated as both positive and
negative modulators of axonal growth; however, the functional properties of only a few …

After injury to the adult central nervous system (CNS), numerous cytokines and growth
factors are released that contribute to reactive gliosis and extracellular matrix production. In …

Chondroitin sulfate (CS) is a member of glycosaminoglycans (GAGs) and has critical
physiological functions. CS is widely applied in medical and clinical fields. Currently, the …

WJulfation of chondroitin sulfateby 3'-phosphoadenosine 5'-phosphosulfate was first
described by D'Abramo and Lipmann (1957). Subsequently, 3'-phosphoadenosine 5' …

Highlights•Chondroitin sulfate–dermatan sulfate (CS–DS) chains modulate Wnt/β-catenin
signaling.•Semaphorin 3A and CS–DS in perineuronal nets are involved in neuronal …