The nuclear factor-kappaB (NF-κB) transcription factors have emerged as major regulators
of programmed cell death (PCD) whether via apoptosis or necrosis. In this context, NF-κB's …

The Rel/NF-κB transcription factors are key regulators of programmed cell death (PCD).
Their activity has significant physiological relevance for normal development and …

During their lifetime, cells encounter many life or death situations that challenge their very
own existence. Their survival depends on the interplay within a complex yet precisely …

The transcription factor nuclear factor κB (NF-κB) is a pleiotropic protein complex that is
activated from a sequestered, cytoplasmic form by pro-inflammatory extracellular signals …

Nuclear factor-κB (NF-κB) is generally viewed as anti-apoptotic and oncogenic, leading to a
quest for its inhibitors. However, recent evidence suggests that in some situations NF-κB …

The imbalance between proliferation and programmed cell death (apoptosis) is one of the
critical cellular events that lead to oncogenesis. While there is no doubt that uncontrolled cell …

The most extensively studied function of NF-κB is its ability to promote cell survival through
induction of target genes, whose products inhibit various aspects of the apoptotic machinery …

NF-κB/Rel transcription factors have recently emerged as crucial regulators of cell survival.
Activation of NF-κB antagonizes programmed cell death (PCD) induced by tumor necrosis …

The role of nuclear factor (NF)-κB in the regulation of apoptosis in normal and cancer cells
has been extensively studied in recent years. Constitutive NF-κB activity in B lymphocytes as …

Apoptosis: Activate NF-κB or die?: Current Biology Skip to Main Content Advertisement Current
Biology This journal offers authors two options (open access or subscription) to publish research …