The potential of low molecular weight heparin to mitigate cytokine storm in severe COVID‐19 patients: a retrospective cohort study

C Shi, C Wang, H Wang, C Yang, F Cai… - Clinical and …, 2020 - Wiley Online Library
On March 11, 2020, the World Health Organization declared its assessment of coronavirus
disease 2019 (COVID‐19) as a global pandemic. However, specific anti‐severe acute …

Beneficial non-anticoagulant mechanisms underlying heparin treatment of COVID-19 patients

B Buijsers, C Yanginlar, ML Maciej-Hulme… - …, 2020 - thelancet.com
Abstract Coronavirus disease-2019 (COVID-19) is associated with severe inflammation in
mainly the lung, and kidney. Reports suggest a beneficial effect of the use of heparin/low …

Role of low-molecular-weight heparin in hospitalized patients with severe acute respiratory syndrome coronavirus 2 pneumonia: a prospective observational study

M Falcone, G Tiseo, G Barbieri, V Galfo… - Open forum …, 2020 - academic.oup.com
Background This study was conducted to evaluate the impact of low-molecular-weight
heparin (LMWH) on the outcome of patients with severe acute respiratory syndrome …

Preliminary experience with low molecular weight heparin strategy in COVID-19 patients

P Paolisso, L Bergamaschi, EC D'Angelo… - Frontiers in …, 2020 - frontiersin.org
Background Heparin administration in COVID-19 patients is recommended by expert
consensus, although evidence about dosage, duration and efficacy are limited. We aim to …

Heparin-induced thrombocytopenia is associated with a high risk of mortality in critical COVID-19 patients receiving heparin-involved treatment

X Liu, X Zhang, Y Xiao, T Gao, G Wang, Z Wang… - MedRxiv, 2020 - medrxiv.org
Background Coronavirus infectious disease 2019 (COVID-19) has developed into a global
pandemic. It is essential to investigate the clinical characteristics of COVID-19 and uncover …

Comprehensive landscape of heparin therapy for COVID-19

C Shi, W Tingting, JP Li, MA Sullivan, C Wang… - Carbohydrate …, 2021 - Elsevier
The pandemic coronavirus disease 2019 (COVID-19), caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading globally …

Use of enoxaparin to counteract COVID-19 infection and reduce thromboembolic venous complications: a review of the current evidence

F Drago, L Gozzo, L Li, A Stella, B Cosmi - Frontiers in pharmacology, 2020 - frontiersin.org
The impact of the COVID-19 pandemic has been dramatic worldwide, with China, Italy, and
now US at its epicenter. Researchers and clinicians are studying and testing different …

Heparin as a therapy for COVID-19: current evidence and future possibilities

JA Hippensteel, WB LaRiviere… - … of Physiology-Lung …, 2020 - journals.physiology.org
Coronavirus disease 2019 (COVID-19), the clinical syndrome associated with infection by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted nearly every …

The use of the anticoagulant heparin and corticosteroid dexamethasone as prominent treatments for COVID-19

HA Braz-de-Melo, SS Faria… - Frontiers in …, 2021 - frontiersin.org
COVID-19 is spreading worldwide at disturbing rates, overwhelming global healthcare.
Mounting death cases due to disease complications highlight the necessity of describing …

Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study

A Di Castelnuovo, S Costanzo… - Thrombosis and …, 2021 - thieme-connect.com
Introduction A hypercoagulable condition was described in patients with coronavirus
disease 2019 (COVID-19) and proposed as a possible pathogenic mechanism contributing …