Chikusetsu saponin IVa regulates glucose uptake and fatty acid oxidation: implications in antihyperglycemic and hypolipidemic effects
Y Li, T Zhang, J Cui, N Jia, Y Wu, M Xi… - Journal of Pharmacy …, 2015 - academic.oup.com
Objectives The aim of this study is to investigate antidiabetic effects and molecular
mechanisms of the chemical Chikusetsu saponin IVa (CHS) that isolated from root bark of A …
mechanisms of the chemical Chikusetsu saponin IVa (CHS) that isolated from root bark of A …
Hypoglycemic and hypolipidemic effects of total saponins from Stauntonia chinensis in diabetic db/db mice
J Xu, S Wang, T Feng, Y Chen… - Journal of cellular and …, 2018 - Wiley Online Library
Stauntonia chinensis DC. has been utilised as a traditional herbal medicine for its anti‐
hyperglycemic characteristic, which has been associated with triterpene saponins. The goal …
hyperglycemic characteristic, which has been associated with triterpene saponins. The goal …
Insulinotropic effect of Chikusetsu saponin IVa in diabetic rats and pancreatic β-cells
J Cui, MM Xi, YW Li, JL Duan, L Wang, Y Weng… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance As a well-known traditional Chinese medicine the root
bark of Aralia taibaiensis has traditionally been used as the medicine considered alleviating …
bark of Aralia taibaiensis has traditionally been used as the medicine considered alleviating …
Antihyperglycemic, hypolipidemic and antioxidant activities of total saponins extracted from Aralia taibaiensis in experimental type 2 diabetic rats
Y Weng, L Yu, J Cui, YR Zhu, C Guo, G Wei… - Journal of …, 2014 - Elsevier
Ethnopharmacological relevance As a well-known traditional Chinese medicine the root
bark of Aralia taibaiensis has multiple pharmacological activities, including relieving …
bark of Aralia taibaiensis has multiple pharmacological activities, including relieving …
[HTML][HTML] Triterpenoid Saponins from Stauntonia chinensis Ameliorate Insulin Resistance via the AMP-Activated Protein Kinase and IR/IRS-1/PI3K/Akt Pathways in …
X Hu, S Wang, J Xu, DB Wang, Y Chen… - International journal of …, 2014 - mdpi.com
Inflammation and oxidative stress play crucial roles in the etiology of type 2 diabetes
mellitus. In this study, we examined the anti-diabetic effects of triterpenoid saponins …
mellitus. In this study, we examined the anti-diabetic effects of triterpenoid saponins …
Anemarrhena asphodeloides Bunge total saponins ameliorate diabetic cardiomyopathy by modifying the PI3K/AKT/HIF-1α pathway to restore glycolytic metabolism
L Zhong, J Li, J Yu, X Cao, J Du, L Liang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Based on the theory of traditional Chinese medicine
(TCM), diabetic cardiomyopathy (DCM) belongs to the category of" Xiaoke disease" …
(TCM), diabetic cardiomyopathy (DCM) belongs to the category of" Xiaoke disease" …
Involvement of the PI3K/AKT pathway in the hypoglycemic effects of saponins from Helicteres isora
AIM OF THE STUDY: Saponins from Helicteres isora have previously been shown to exert
antidiabetic effects. The present study explored the underlying mechanisms in C2C12 …
antidiabetic effects. The present study explored the underlying mechanisms in C2C12 …
Platycodi radix saponin inhibits α-glucosidase in vitro and modulates hepatic glucose-regulating enzyme activities in C57BL/KsJ-db/db mice
JS Lee, MS Choi, KI Seo, J Lee, HI Lee, JH Lee… - Archives of pharmacal …, 2014 - Springer
This study investigated anti-diabetic activity of a concentrated saponin fraction from
Platycodi radix (SK1) in C57BL/KsJ-db/db mice and its underlying mechanism. Mice were …
Platycodi radix (SK1) in C57BL/KsJ-db/db mice and its underlying mechanism. Mice were …
Effects of Panax quinquefolius saponin of stem and leaf on glucose-lipid metabolism and insulin signal transduction in insulin resistant model adipocytes
Y Zhang, KJ Chen, LH Yang - Zhongguo Zhong xi yi jie he za zhi …, 2010 - europepmc.org
Objective To observe the effects of panax quinquefolius saponin (PQS) of stem and leaf on
glucose-lipid metabolism and insulin signal transduction in the insulin resistant model of …
glucose-lipid metabolism and insulin signal transduction in the insulin resistant model of …
Potent Effects of the Total Saponins from Dioscorea nipponica Makino Against Streptozotocin‐Induced Type 2 Diabetes Mellitus in Rats
H Yu, L Zheng, L Xu, L Yin, Y Lin, H Li… - Phytotherapy …, 2015 - Wiley Online Library
The aim of the present paper was to investigate the effects and possible mechanisms of the
total saponins from Dioscorea nipponica Makino (TSDN) against type 2 diabetes mellitus …
total saponins from Dioscorea nipponica Makino (TSDN) against type 2 diabetes mellitus …