To clarify the lower urinary tract function in mice, we compared bladder and urethral activity
between rats and mice with or without spinal cord injury (SCI). Female Sprague-Dawley rats …

OBJECTIVES: To investigate the effect of long-term administration of oxybutynin on afferent
input from the bladder by evaluating c-Fos expression in the spinal cord. METHODS: Using …

Study Type–Aetiology (case control) Level of Evidence 3c What's known on the subject? and
What does the study add? Neurogenic detrusor overactivity (NDO) and autonomic …

Purpose Whereas many studies have focused on the vesical changes of the α1 adrenergic
receptor (AR) subtypes in partial outlet obstruction, few studies have addressed the …

Neurally intact (NI) rats and chronic spinal cord injured (SCI) rats were studied to determine
how activation of mechanosensory or cholinergic receptors in the bladder urothelium evokes …

Introduction Sacral neuromodulation has been considered as an effective treatment option
for various types of chronic voiding dysfunction, but the mechanism of action has not been …

This review article aims to summarize the recent advancement in basic research on lower
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …

Aims We investigated the relationship between IL‐1β and morphological and functional
changes following partial bladder outlet obstruction (pBOO). Methods Female wild‐type …

Background We investigated the regulation of urinary bladder function by electrical
stimulation of the L6 spinal nerve (SN) using cystometry in normal rats and in rats with …

What's known on the subject? and What does the study add? It is well known that urinary
bladder sensation requires the activation by ATP of ionotropic purinergic P2X3/P2X2/3 …