Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells requires protein kinase C‐α activation

A Jong, CH Wu, NV Prasadarao… - Cellular …, 2008 - Wiley Online Library
Pathogenic fungus Cryptococcus neoformans has a predilection for the central nervous
system causing devastating meningoencephalitis. Traversal of C. neoformans across the …

Microevolution of a Standard Strain ofCryptococcus neoformans Resulting in Differences in Virulence and Other Phenotypes

SP Franzot, J Mukherjee, R Cherniak… - Infection and …, 1998 - Am Soc Microbiol
Cryptococcus neoformans is a major fungal pathogen for patients with debilitated immune
systems. However, no information is available on the stability of virulence or of phenotypes …

Experimental model of intracerebral infection with Cryptococcus neoformans: roles of phagocytes and opsonization

E Blasi, R Barluzzi, R Mazzolla, P Mosci… - Infection and …, 1992 - Am Soc Microbiol
A murine model of intracerebral (ic) infection with Cryptococcus neoformans in which naive
mice receiving an ic fungal inoculation developed a severe disease has been established …

[引用][C] Cryptococcus neoformans.

RD Diamond - 1990 - cabidigitallibrary.org
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The cause and effect of Cryptococcus interactions with the host

ER Ballou, SA Johnston - Current opinion in microbiology, 2017 - Elsevier
Upon Cryptococcus neoformans infection of the host lung, the fungus enters a nutrient poor
environment and must adapt to a variety of host-specific stress conditions (temperature …

Cryptococcus neoformans meningitis in the rat.

DL Goldman, A Casadevall, Y Cho… - … investigation; a journal of …, 1996 - europepmc.org
The primary clinical manifestation of Cryptococcus neoformans infection in humans is
meningoencephalitis. To study the defense mechanisms that participate in the host …

Basic principles of the virulence of Cryptococcus

O Zaragoza - Virulence, 2019 - Taylor & Francis
Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

Cryptococcus neoformans-Derived Microvesicles Enhance the Pathogenesis of Fungal Brain Infection

SH Huang, CH Wu, YC Chang, KJ Kwon-Chung… - PloS one, 2012 - journals.plos.org
Cryptococcal meningoencephalitis is the most common fungal disease in the central
nervous system. The mechanisms by which Cryptococcus neoformans invades the brain are …

Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence

KL Ormerod, CA Morrow, EWL Chow… - G3: Genes …, 2013 - academic.oup.com
The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …