Systematic screening for congenital hypothyroidism in the newborn was introduced some 15
years ago. The main objective was the prevention of mental retardation due to thyroid …

Much attention has been directed recently to congenital hypothyroidism, the classic and
most common endocrine disease of paediatric medicine. This is the result of the introduction …

The task of defining'optimal management'of any condition presents a considerable
challenge in today's climate of'consensus management'and'best practice', particularly in …

Intellectual and physical development of 23 children was correlated with age at initial
treatment and with dosage of thyroid replacement therapy. Seven children, treated …

THYROID DEFICIENCY during childhood often gives rise to physical signs which can be
readily recognised. Growth is delayed, the ossification of the epiphyseal cartilages and the …

The horror of cretinism and the joy of its treatment can never havebeen expressed more
vividly than by William Osler, writing in 1897 soon after the effect of thyroid replacement was …

Since the introduction of screening programs for congenital hypothyroidism, transient
disturbances of thyroid function, especially transient congenital hypothyroidism and …

The clinical and laboratory characteristics of infants with neonatal hypothyroidism, and the
age at which treatment was started are reviewed. The incidence of primary hypothyroidism …

Serum thyroid stimulating hormone and thyroxine concentrations were monitored in 42
infants who had been treated for congenital hypothyroidism. Serum thyroid stimulating …

Recent advances in science and technology have led to the capability of early screening of
newborn infants for congenital hypothyroidism. Preliminary screening programs in North …