Translating insights from the cancer genome into clinical practice
L Chin, JW Gray - Nature, 2008 - nature.com
Cancer cells have diverse biological capabilities that are conferred by numerous genetic
aberrations and epigenetic modifications. Today's powerful technologies are enabling these …
aberrations and epigenetic modifications. Today's powerful technologies are enabling these …
Cancer genomics: from discovery science to personalized medicine
L Chin, JN Andersen, PA Futreal - Nature medicine, 2011 - nature.com
Recent advances in genome technologies and the ensuing outpouring of genomic
information related to cancer have accelerated the convergence of discovery science and …
information related to cancer have accelerated the convergence of discovery science and …
How cancer genomics is transforming diagnosis and treatment
B Nogrady - Nature, 2020 - nature.com
When cancer was first described by the ancient Greek physician Hippocrates, he identified
just two forms: the non-ulcer-forming carcinos and the ulcer-forming carcinoma. In the late …
just two forms: the non-ulcer-forming carcinos and the ulcer-forming carcinoma. In the late …
[HTML][HTML] International network of cancer genome projects
International Cancer Genome Consortium - Nature, 2010 - ncbi.nlm.nih.gov
Abstract The International Cancer Genome Consortium (ICGC) was launched to coordinate
large-scale cancer genome studies in tumors from 50 different cancer types and/or subtypes …
large-scale cancer genome studies in tumors from 50 different cancer types and/or subtypes …
Cancer: looking outside the genome
J Folkman, P Hahnfeldt, L Hlatky - Nature Reviews Molecular Cell …, 2000 - nature.com
The 'gene-centric'approach has produced a wealth of information about the origins and
progression of cancer, and investigators seek a full compilation of altered gene expressions …
progression of cancer, and investigators seek a full compilation of altered gene expressions …
[HTML][HTML] Cancer complexity slows quest for cure
EC Hayden - Nature, 2008 - siliconinvestor.com
The controversial Cancer Genome Atlas, run by the US National Institutes of Health, is
analysing genetic and epigenetic changes in cancers. Still in its pilot phase, the project …
analysing genetic and epigenetic changes in cancers. Still in its pilot phase, the project …
The causes and consequences of genetic heterogeneity in cancer evolution
Recent studies have revealed extensive genetic diversity both between and within tumours.
This heterogeneity affects key cancer pathways, driving phenotypic variation, and poses a …
This heterogeneity affects key cancer pathways, driving phenotypic variation, and poses a …
Exploring the genomes of cancer cells: progress and promise
MR Stratton - science, 2011 - science.org
The description and interpretation of genomic abnormalities in cancer cells have been at the
heart of cancer research for more than a century. With exhaustive sequencing of cancer …
heart of cancer research for more than a century. With exhaustive sequencing of cancer …
Translating genomics for precision cancer medicine
R Sameek, AM Chinnaiyan - Annual review of genomics and …, 2014 - annualreviews.org
The Human Genome Project not only provided the essential reference map for the human
genome but also stimulated the development of technology and analytic tools to process …
genome but also stimulated the development of technology and analytic tools to process …
[HTML][HTML] Epigenetics: Unravelling the cancer code
V Brower - Nature, 2011 - nature.com
Epigenetics: Unravelling the cancer code | Nature Skip to main content Thank you for visiting
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