Suppression of detrusor-sphincter dysynergia by GABA-receptor activation in the lumbosacral spinal cord in spinal cord-injured rats
M Miyazato, K Sasatomi, S Hiragata… - American Journal …, 2008 - journals.physiology.org
We investigated the effects of intrathecal application of GABAA-or GABAB-receptor agonists
on detrusor-sphincter dyssynergia (DSD) in spinal cord transection (SCT) rats. Adult female …
on detrusor-sphincter dyssynergia (DSD) in spinal cord transection (SCT) rats. Adult female …
GABA receptor activation in the lumbosacral spinal cord decreases detrusor overactivity in spinal cord injured rats
M Miyazato, K Sasatomi, S Hiragata… - The Journal of …, 2008 - auajournals.org
Purpose: We investigated the effects of intrathecal application of γ-aminobutyric acid A and
B receptor agonists on detrusor overactivity in spinal cord injured rats. Materials and …
B receptor agonists on detrusor overactivity in spinal cord injured rats. Materials and …
α1D-Adrenoceptor blockade increases voiding efficiency by improving external urethral sphincter activity in rats with spinal cord injury
H Ishida, H Yamauchi, H Ito, H Akino… - American Journal of …, 2016 - journals.physiology.org
Ideal therapy for lower urinary tract dysfunction in patients with spinal cord injury (SCI)
should decrease detrusor overactivity, thereby promoting urine storage at low intravesical …
should decrease detrusor overactivity, thereby promoting urine storage at low intravesical …
Altered glutamate receptor function during recovery of bladder detrusor-external urethral sphincter coordination in a rat model of spinal cord injury
V Pikov, JR Wrathall - Journal of Pharmacology and Experimental …, 2002 - ASPET
Coordination of the bladder detrusor and the external urethral sphincter is a supraspinally
controlled reflex that is essential for efficient micturition. This coordination is permanently lost …
controlled reflex that is essential for efficient micturition. This coordination is permanently lost …
Influence of spinal cord injury on the morphology of bladder afferent and efferent neurons
MN Kruse, LA Bray, WC De Groat - Journal of the autonomic nervous …, 1995 - Elsevier
Severe micturition dysfunction can occur following spinal cord injury (SCI) due to abnormal
contractions of the urethral sphincter during bladder contractions (bladder/sphincter …
contractions of the urethral sphincter during bladder contractions (bladder/sphincter …
Combinational effects of muscarinic receptor inhibition and β3‐adrenoceptor stimulation on neurogenic bladder dysfunction in rats with spinal cord injury
N Wada, T Shimizu, S Takai, N Shimizu… - Neurourology and …, 2017 - Wiley Online Library
Aims To investigate the effects of combined therapy with an anticholinergic agent and a β3‐
adrenoceptor agonist on bladder dysfunction and proliferation‐related molecule expression …
adrenoceptor agonist on bladder dysfunction and proliferation‐related molecule expression …
Roles of Glycinergic and Gamma‐aminobutyric‐ergic Mechanisms in the Micturition Reflex in Rats
M Miyazato, N Yoshimura, S Nishijima… - LUTS: Lower Urinary …, 2009 - Wiley Online Library
The micturition reflex is one of the autonomic reflexes mediated by the spinobulbospinal
reflex pathway that passes through the pontine micturition center. In the central nervous …
reflex pathway that passes through the pontine micturition center. In the central nervous …
Rectal distention inhibits the spinal micturition reflex via glycinergic or GABAergic mechanisms in rats with spinal cord injury
M Miyazato, K Sugaya, S Nishijima, M Morozumi… - Urologia …, 2005 - karger.com
Background: We examined the influence of rectal distention on the spinal micturition reflex
and the mechanism underlying its inhibition of bladder contraction. Methods: Fourteen …
and the mechanism underlying its inhibition of bladder contraction. Methods: Fourteen …
Suppression of detrusor-sphincter dyssynergia by immunoneutralization of nerve growth factor in lumbosacral spinal cord in spinal cord injured rats
S Seki, K Sasaki, Y Igawa, O Nishizawa… - The Journal of …, 2004 - auajournals.org
Purpose: We investigated the effects of intrathecal application of nerve growth factor (NGF)
antibodies (NGF-Abs) and desensitization of C-fiber afferent pathways by capsaicin …
antibodies (NGF-Abs) and desensitization of C-fiber afferent pathways by capsaicin …
Rectal distention inhibits bladder activity via glycinergic and GABAergic mechanisms in rats
M Miyazato, K Sugaya, S Nishijima… - The Journal of …, 2004 - auajournals.org
Purpose: We examined the influence of rectal distention on the spinobulbospinal micturition
reflex and the mechanism underlying the inhibition of bladder contraction. Materials and …
reflex and the mechanism underlying the inhibition of bladder contraction. Materials and …