Molecular targeting strategies for cancer therapy are distinct from conventional
chemotherapy and radiotherapy in their potential to provide increased tumor specificity. One …

The discovery that signaling by the epidermal growth factor receptor (EGFR) plays a key role
in tumorigenesis prompted efforts to target this receptor in anticancer therapy. Two different …

The epidermal growth factor receptor (EGFR) is overexpressed in many solid tumours.
Targeting EGFR is emerging as a potential strategy to incorporate into cancer treatment …

The epidermal growth factor receptor (EGFR) is expressed in a wide variety of solid tumours.
It has been demonstrated that the EGFR-associated signaling pathway plays an important …

Novel therapeutic agents that target the epidermal growth factor receptor (EGFR) constitute
an important addition to the therapeutic armamentarium for the treatment of metastatic …

Molecular inhibition of epidermal growth factor receptor (EGFR/HER1) signaling is under
active investigation as a promising cancer treatment strategy. We examined the potency of …

Background: Agents targeting the epidermal growth factor (EGFR)-mediated signaling
pathway are used in the treatment of various solid tumors, including lung, breast, pancreatic …

Epidermal growth factor receptor (EGFR) signaling inhibition represents a highly promising
arena for the application of molecularly targeted cancer therapies. Evolving from several …

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase of the ErbB
receptor family that is abnormally activated in many epithelial tumors. The aberrant …

Aberrant signalling through the epidermal growth factor receptor (EGFR) plays a major role
in the progression and maintenance of the malignant phenotype and the receptor is …