Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis

F Marra, A Gastaldelli, GS Baroni, G Tell… - Trends in molecular …, 2008 - cell.com
Non-alcoholic steatohepatitis (NASH), a cause of cirrhosis and hepatocellular carcinoma, is
characterized by fatty infiltration of the liver, inflammation, hepatocellular damage and …

Investigating the link between ketogenic diet, NAFLD, mitochondria, and oxidative stress: a narrative review

A Paoli, G Cerullo - Antioxidants, 2023 - mdpi.com
Together with the global rise in obesity and metabolic syndrome, the prevalence of
individuals who suffer from nonalcoholic fatty liver disease (NAFLD) has risen dramatically …

Non-alcoholic fatty liver disease pathogenesis: the present and the future

S Petta, C Muratore, A Craxi - Digestive and Liver Disease, 2009 - Elsevier
Non-alcoholic fatty liver disease is the clinical hepatic expression of metabolic syndrome.
The prevalence of non-alcoholic fatty liver disease is around 20–30%, and with a rapid …

[HTML][HTML] Metabolic drivers of non-alcoholic fatty liver disease

KK Bence, MJ Birnbaum - Molecular metabolism, 2021 - Elsevier
Background The incidence of non-alcoholic fatty liver disease (NAFLD) is rapidly increasing
worldwide parallel to the global obesity epidemic. NAFLD encompasses a range of liver …

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

DH Ipsen, J Lykkesfeldt, P Tveden-Nyborg - Cellular and molecular life …, 2018 - Springer
Non-alcoholic fatty liver disease (NAFLD) is currently the world's most common liver
disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic …

The role of the lipogenic pathway in the development of hepatic steatosis

C Postic, J Girard - Diabetes & metabolism, 2008 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) represents a wide spectrum of diseases, ranging
from simple fatty liver (hepatic steatosis) through steatosis with inflammation and necrosis to …

The metabolic basis of nonalcoholic steatohepatitis

MV Chakravarthy… - … , diabetes & metabolism, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease and is
associated with significant morbidity and mortality worldwide, with a high incidence in …

[HTML][HTML] Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis

S Asif, RY Kim, T Fatica, J Sim, X Zhao, Y Oh… - Molecular …, 2022 - Elsevier
Objective Aberrant ketogenesis is correlated with the degree of steatosis in non-alcoholic
fatty liver disease (NAFLD) patients, and an inborn error of ketogenesis (mitochondrial HMG …

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

E Buzzetti, M Pinzani, EA Tsochatzis - Metabolism, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …

[HTML][HTML] The cellular pathways of liver fibrosis in non-alcoholic steatohepatitis

N Méndez-Sánchez, A Valencia-Rodríguez… - Annals of …, 2020 - ncbi.nlm.nih.gov
Non-alcoholic steatohepatitis (NASH) is considered the advanced stage of non-alcoholic
fatty liver disease (NAFLD). It is characterized by liver steatosis, inflammation and different …