Non-alcoholic fatty liver disease, obesity and the metabolic syndrome

P Dietrich, C Hellerbrand - Best practice & research Clinical …, 2014 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is now recognized as the most common cause of
chronic liver disease worldwide. Its prevalence has increased to more than 30% of adults in …

[HTML][HTML] New targets for NAFLD

L Parlati, M Régnier, H Guillou, C Postic - JHEP Reports, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease
worldwide. It is characterised by steatosis, liver inflammation, hepatocellular injury and …

[HTML][HTML] Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)

X Xu, KL Poulsen, L Wu, S Liu, T Miyata… - Signal transduction and …, 2022 - nature.com
Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …

[HTML][HTML] Pathogenesis and therapeutic approaches for non-alcoholic fatty liver disease

H Yoon, BS Cha - World journal of hepatology, 2014 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease affects approximately one-third of the population worldwide,
and its incidence continues to increase with the increasing prevalence of other metabolic …

An overview of lipid metabolism and nonalcoholic fatty liver disease

K Pei, T Gui, D Kan, H Feng, Y Jin… - BioMed Research …, 2020 - Wiley Online Library
The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major
abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or …

[HTML][HTML] Natural progression of non-alcoholic steatohepatitis to hepatocellular carcinoma

D Ramai, W Tai, M Rivera, A Facciorusso, N Tartaglia… - Biomedicines, 2021 - mdpi.com
Non-alcoholic steatohepatitis (NASH) is a chronic and progressive form of non-alcoholic
fatty liver disease (NAFLD). Its global incidence is increasing which makes NASH an …

Nonalcoholic steatohepatitis

A Suzuki, AM Diehl - Annual review of medicine, 2017 - annualreviews.org
Nonalcoholic steatohepatitis (NASH) has become a major cause of cirrhosis and liver-
related deaths worldwide. NASH is strongly associated with obesity and the metabolic …

[HTML][HTML] From NASH to diabetes and from diabetes to NASH: mechanisms and treatment options

A Gastaldelli, K Cusi - JHEP reports, 2019 - Elsevier
The worldwide prevalence of non-alcoholic fatty liver disease (NAFLD) is estimated to have
reached 25% or more in adults. NAFLD is prevalent in obese individuals, but may also affect …

Bioactive lipid species and metabolic pathways in progression and resolution of nonalcoholic steatohepatitis

G Musso, M Cassader, E Paschetta, R Gambino - Gastroenterology, 2018 - Elsevier
The prevalence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, yet there
are no effective treatments. A decade has passed since the initial lipidomics analyses of liver …

The role of fatty acids in the development and progression of nonalcoholic fatty liver disease

CL Gentile, MJ Pagliassotti - The Journal of nutritional biochemistry, 2008 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as a serious obesity-related disorder.
NAFLD encompasses a wide spectrum of hepatic derangements ranging from a surfeit of fat …