Patients with polycystic ovary syndrome have lower levels of IgM anti-phosphorylcholine antibodies than healthy women
M Gingnell, I Dahlbom, Å Lindholm… - Gynecological …, 2011 - Taylor & Francis
Introduction. IgM antibodies against phosphorylcholine (IgM anti-PC) are natural
autoantibodies, possibly exerting one of the atheroprotective functions of the immune …
autoantibodies, possibly exerting one of the atheroprotective functions of the immune …
Low levels of IgM antibodies against phosphorylcholine-A increase mortality risk in patients undergoing haemodialysis
JJ Carrero, X Hua, P Stenvinkel… - Nephrology Dialysis …, 2009 - academic.oup.com
Background. Atherosclerosis is an inflammatory disease where oxidized low-density
lipoprotein may play an important role through phosphorylcholine (PC)-exposing …
lipoprotein may play an important role through phosphorylcholine (PC)-exposing …
Levels of natural IgM antibodies against phosphorylcholine in healthy individuals and in patients undergoing isolated limb perfusion
ND Padilla, C Ciurana, J van Oers, AC Ogilvie… - Journal of …, 2004 - Elsevier
Natural IgM antibodies against phosphorylcholine (anti-Pc IgM) resemble C-reactive protein
(CRP) regarding specificity and have gained increasing attention because of their supposed …
(CRP) regarding specificity and have gained increasing attention because of their supposed …
[HTML][HTML] Antibodies against phosphorylcholine in hospitalized versus non-hospitalized obese subjects
Obesity associates with reduced life expectancy, type 2 diabetes, hypertension and
cardiovascular disease, and is characterized by chronic inflammation. Phosphorylcholine …
cardiovascular disease, and is characterized by chronic inflammation. Phosphorylcholine …
a fully human monoclonal IgG phosphorylcholine antibody prevents accelerated atherosclerosis in mice
K Pettersson, MM Ewing, MR de Vries, R Atout… - 2011 - Am Heart Assoc
Background: Serum contains natural IgM antibodies against the phosphorylcholine
headgroup of phosphatidylcholine (anti-PC). Low levels are associated with an increased …
headgroup of phosphatidylcholine (anti-PC). Low levels are associated with an increased …
Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease
CA Gleissner, C Erbel, J Haeussler… - Clinical Research in …, 2015 - Springer
Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased
incidence of adverse events in coronary artery disease (CAD). The underlying mechanisms …
incidence of adverse events in coronary artery disease (CAD). The underlying mechanisms …
The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells
PX Shaw, CS Goodyear, MK Chang… - The Journal of …, 2003 - journals.aai.org
Abs specific for phosphorylcholine (PC) are known to contribute to the immune defense
against a variety of microbial infections. To assess for other types of binding interactions, we …
against a variety of microbial infections. To assess for other types of binding interactions, we …
Autoantibodies to phosphorylcholine and cardiovascular outcomes in patients with acute coronary syndromes in the ATLAS ACS-TIMI 46 trial
BJ Geller, JL Mega, DA Morrow, J Guo… - Journal of thrombosis …, 2014 - Springer
Atherogenesis is a complex inflammatory process stemming from the accumulation and
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …
Phosphorylcholine-targeting immunization reduces atherosclerosis
G Caligiuri, J Khallou-Laschet, M Vandaele… - Journal of the American …, 2007 - jacc.org
Objectives: The present study evaluated the effect of phosphorylcholine (PC) immunization
on the extent of experimental atherosclerosis. Background: Immunization against oxidized …
on the extent of experimental atherosclerosis. Background: Immunization against oxidized …
Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension
J Su, A Georgiades, R Wu, T Thulin, U de Faire… - Atherosclerosis, 2006 - Elsevier
OBJECTIVE: To determine the importance of antibodies against phosphorylcholine (PC) and
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS …
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS …