Novel Autoimmune IgM Antibody Attenuates Atherosclerosis in IgM Deficient Low-Fat Diet–Fed, but Not Western Diet–Fed Apoe–/– Mice

OA Cherepanova, P Srikakulapu… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Oxidized phospholipids (OxPL), such as the oxidized derivatives of 1-palmitoyl-2-
arachidonoyl-sn-glycero-3-phosphorylcholine, 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3 …

OxLDL/β2-glycoprotein I complex as a pro-atherogenic autoantigen. Is atherosclerosis an autoimmune disease?

P Kraml - Vnitrni Lekarstvi, 2016 - europepmc.org
Oxidation of atherogenic low-density lipoproteins (LDL) plays a key role in the pathogenesis
of atherosclerosis. Oxidation stress and inflammation are closely interrelated and they can …

Antiphospholipid syndrome: pathogenic mechanisms

G Espinosa, R Cervera, J Font, Y Shoenfeld - Autoimmunity Reviews, 2003 - Elsevier
Despite the strong association between antiphospholipid antibodies (aPL) and thrombosis,
the pathogenic role of aPL in the development of thrombosis has not been fully elucidated …

Anti-phospholipid autoantibodies in human diseases

R Qin, H Wu, H Guan, C Tang, Z Zheng, C Deng… - Clinical …, 2023 - Elsevier
Anti-phospholipid autoantibodies are a group of antibodies that can specifically bind to
anionic phospholipids and phospholipid protein complexes. Recent studies have reported …

Infections and the antiphospholipid syndrome

M García-Carrasco, C Galarza-Maldonado… - Clinical reviews in …, 2009 - Springer
Currently, the origin of autoimmune diseases is considered to be multifactorial. Genetic
predisposition, immune system malfunction or even backfire, hormonal regulation, and …

Pathogenesis of the antiphospholipid syndrome: an additional example of the mosaic of autoimmunity

PL Meroni - Journal of autoimmunity, 2008 - Elsevier
The antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by
an adaptive immune response against self-PL-binding proteins ending in the production of …

Cofactor-independent antiphospholipid antibodies: implications for pathogenesis, diagnosis, and treatment of antiphospholipid syndrome

KJ Lackner, N Müller-Calleja - Hämostaseologie, 2019 - thieme-connect.com
The antiphospholipid syndrome (APS) has occupied haemostaseologists, rheumatologists
and obstetricians since its initial description 35 years ago. Its name has been coined …

Cardiovascular disease risk in antiphospholipid syndrome: Thrombo-inflammation and atherothrombosis

MG Tektonidou - Journal of Autoimmunity, 2022 - Elsevier
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence
of antiphospholipid antibodies (aPL)(lupus anticoagulant, anticardiolipin antibodies and anti …

Sphingosylphosphorylcholine stimulates CCL2 production from human umbilical vein endothelial cells

HY Lee, SY Lee, SD Kim, JW Shim, HJ Kim… - The Journal of …, 2011 - journals.aai.org
Sphingosylphosphorylcholine (SPC) is a component of high-density lipoprotein particles.
We investigated the functional role of SPC in HUVECs. SPC stimulation induced production …

What are the Target Cells and Receptors that are Recognized by Antiphospholipid Antibodies?

PG de Groot, E Raschi, KR McCrae… - … Syndrome: Insights and …, 2012 - Springer
The antiphospholipid syndrome (APS) is a noninflammatory autoimmune disease defined by
the presence of antiphospholipid autoantibodies (aPL) in plasma of patients with venous …