[HTML][HTML] Significant difference of immune cell fractions and their correlations with differential expression genes in Parkinson's disease

Y Huang, H Liu, J Hu, C Han, Z Zhong… - Frontiers in Aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is the second most neurodegenerative disease in the world. T cell
infiltration in the central nervous system (CNS) has provided insights that the peripheral …

[HTML][HTML] Immune profiling of Parkinson's disease revealed its association with a subset of infiltrating cells and signature genes

X Zhang, Z Shao, S Xu, Q Liu, C Liu, Y Luo… - Frontiers in Aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is an age-related and second most common neurodegenerative
disorder. In recent years, increasing evidence revealed that peripheral immune cells might …

[HTML][HTML] Association of immune cell traits with Parkinson's disease: a Mendelian randomization study

Z Song, W Li, Y Han, Y Xu, H Ding… - Frontiers in Aging …, 2024 - frontiersin.org
Background Immunity and neuroinflammation play crucial roles in the pathogenesis of
Parkinson's disease (PD). Nonetheless, prior investigations into the correlation between …

[HTML][HTML] Inflammation and regulatory T cell genes are differentially expressed in peripheral blood mononuclear cells of Parkinson's disease patients

Z Karaaslan, ÖT Kahraman, E Şanlı, HA Ergen… - Scientific reports, 2021 - nature.com
Our aim was to identify the differentially expressed genes (DEGs) in peripheral blood
mononuclear cells (PBMC) of Parkinson's disease (PD) patients and healthy controls by …

[HTML][HTML] Identification of immune-related hub genes in Parkinson's disease

L Chen, Y Wang, J Huang, B Hu, W Huang - Frontiers in Genetics, 2022 - frontiersin.org
Background: Parkinson's disease (PD) is a common, age-related, and progressive
neurodegenerative disease. Growing evidence indicates that immune dysfunction plays an …

[HTML][HTML] Causal role of immune cells on risk of Parkinson's disease: a Mendelian randomization study

J Gu, Y Qiao, S Cong - Frontiers in Aging Neuroscience, 2024 - frontiersin.org
Background Previous observational studies have suggested a correlation between immune
cells and Parkinson's disease (PD), yet specific investigations into the causal relationship …

[HTML][HTML] Novel diagnostic biomarkers related to immune infiltration in Parkinson's disease by bioinformatics analysis

P Zhang, L Zhao, H Li, J Shen, H Li… - Frontiers in Neuroscience, 2023 - frontiersin.org
Background Parkinson's disease (PD) is Pengfei Zhang Liwen Zhao Pengfei Zhang Liwen
Zhao a common neurological disorder involving a complex relationship with immune …

[HTML][HTML] Cytokine and chemokine map of peripheral specific immune cell subsets in Parkinson's disease

SS Jiang, YL Wang, QH Xu, LY Gu, RQ Kang… - npj Parkinson's …, 2023 - nature.com
Peripheral immune cells play a vital role in the development of Parkinson's disease (PD).
However, their cytokine and chemokine secretion functions remain unclear. Therefore, we …

[HTML][HTML] Immune cell activation in the cerebrospinal fluid of patients with Parkinson's disease

JB Schröder, M Pawlowski, G Meyer zu Hörste… - Frontiers in …, 2018 - frontiersin.org
Background: Parkinson's disease (PD) is a common neurodegenerative disorder. The
contribution of the immune system to its pathogenesis remains incompletely understood …

[HTML][HTML] Integrative analysis of potential biomarkers and immune cell infiltration in Parkinson's disease

X Chen, W Cao, Y Zhuang, S Chen, X Li - Brain Research Bulletin, 2021 - Elsevier
Background Parkinson's disease (PD) is a common neurodegenerative disease in the
elderly population. However, there are no reliable diagnostic biomarkers for PD, and the …