Differential proteomic analysis of astrocytes and astrocytes-derived extracellular vesicles from control and Rai knockout mice: insights into the mechanisms of …
T Montecchi, E Shaba, D De Tommaso… - International Journal of …, 2021 - mdpi.com
Reactive astrocytes are a hallmark of neurodegenerative disease including multiple
sclerosis. It is widely accepted that astrocytes may adopt alternative phenotypes depending …
sclerosis. It is widely accepted that astrocytes may adopt alternative phenotypes depending …
Elusive roles for reactive astrocytes in neurodegenerative diseases
L Ben Haim, MA Carrillo-de Sauvage… - Frontiers in cellular …, 2015 - frontiersin.org
Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory
response. They become reactive in response to virtually all pathological situations in the …
response. They become reactive in response to virtually all pathological situations in the …
Targeting neuroprotective functions of astrocytes in neuroimmune diseases
A Klegeris - Expert Opinion on Therapeutic Targets, 2021 - Taylor & Francis
Astrocytes are the most abundant non-neuronal cells of the central nervous system (CNS)
and are vital for brain homeostasis. This article considers the neuroimmune response, an …
and are vital for brain homeostasis. This article considers the neuroimmune response, an …
Elusive roles for reactive astrocytes in neurodegenerative diseases.
MA Carrillo-de Sauvage, K Ceyzériat… - Frontiers in Cellular …, 2015 - europepmc.org
Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory
response. They become reactive in response to virtually all pathological situations in the …
response. They become reactive in response to virtually all pathological situations in the …
Astrocytes in multiple sclerosis—Essential constituents with diverse multifaceted functions
R Aharoni, R Eilam, R Arnon - International journal of molecular sciences, 2021 - mdpi.com
In multiple sclerosis (MS), astrocytes respond to the inflammatory stimulation with an early
robust process of morphological, transcriptional, biochemical, and functional remodeling …
robust process of morphological, transcriptional, biochemical, and functional remodeling …
Glia in neurodegeneration: the housekeeper, the defender and the perpetrator
Over the past decade, research has unveiled the intimate relationship between
neuroinflammation and neurodegeneration. Microglia and astrocytes react to brain insult by …
neuroinflammation and neurodegeneration. Microglia and astrocytes react to brain insult by …
Insights into the protective role of immunity in neurodegenerative disease
C Comi, G Tondo - Neural regeneration research, 2017 - journals.lww.com
The immune system (IS) is set to provide protection against pathogens, surveillance against
tumor cells and promotion of healing. Such functions can be efficiently performed thanks to …
tumor cells and promotion of healing. Such functions can be efficiently performed thanks to …
Protective functions of reactive astrocytes following central nervous system insult
M Linnerbauer, V Rothhammer - Frontiers in immunology, 2020 - frontiersin.org
Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …
Astrocytes: initiators of and responders to inflammation
We are in the midst of a glial renaissance; astrocytes, essential for brain homeostasis and
neuroprotection, have experienced resurgence in focused analyses. New roles in synaptic …
neuroprotection, have experienced resurgence in focused analyses. New roles in synaptic …
Astrocytes: heterogeneous and dynamic phenotypes in neurodegeneration and innate immunity
C Cunningham, A Dunne… - The …, 2019 - journals.sagepub.com
Astrocytes are the most numerous cell type in the brain and perform several essential
functions in supporting neuronal metabolism and actively participating in neural circuit and …
functions in supporting neuronal metabolism and actively participating in neural circuit and …