Background: Currently recommended whole cell pertussis (wP) vaccination schedule for
children includes a 3-dose primary schedule, and at least one booster dose. When …

Background: Currently recommended whole cell pertussis (wP) vaccination schedule for
children includes a 3-dose primary schedule, and at least one booster dose. When …

Background Robust routine immunization schedules for pertussis-containing vaccines have
been applied for years, but pertussis outbreaks remain a worldwide problem. This study …

Background. Acellular pertussis (aP) and whole-cell (wP) pertussis vaccines are presumed
to have similar short-term (< 3 years after completion of the primary series) efficacy …

Background Acellular pertussis vaccine studies postulate that waning protection, particularly
after the adolescent booster, is a major contributor to the increasing US pertussis incidence …

Objective Countries routinely offering acellular pertussis vaccine, where long-term protection
is not sustained, have the challenge of selecting an optimal schedule to minimise disease …

Background: Due to the resurgence of pertussis, many countries have revised the pertussis
immunization schedules and recommended booster doses of pertussis component vaccine …

Background Acellular pertussis vaccines were initially licensed based on placebo-controlled
efficacy trials, but such trials are no longer ethical. The effectiveness of current pertussis …

Universal pertussis vaccination continues to prevent a previously common and serious
disease of childhood. Despite widespread gains in disease control, pertussis has not been …

Background Pertussis is a highly infectious disease and an important public health concern.
The main aim of pertussis vaccination is to reduce the risk of severe pertussis in infants and …