Effect of bezafibrate on monocyte cytokine release and systemic inflammation in patients with impaired fasting glucose

R Krysiak, B Okopien - The Journal of Clinical Pharmacology, 2011 - Wiley Online Library
This study assessed the effect of bezafibrate on monocyte secretory function and systemic
inflammation in patients with impaired fasting glucose (IFG), comparing this effect with that …

Metabolic and monocyte-suppressing actions of fenofibrate in patients with mixed dyslipidemia and early glucose metabolism disturbances

R Krysiak, A Stachura-Kułach, B Okopień - Pharmacological Reports, 2010 - Springer
The aim of this study was to compare the action of fenofibrate on monocyte cytokine release
between patients with isolated mixed dyslipidemia and dyslipidemia coexisting …

Effects of short-term fenofibrate treatment on circulating markers of inflammation and hemostasis in patients with impaired glucose tolerance

B Okopien, R Krysiak, ZS Herman - The Journal of Clinical …, 2006 - academic.oup.com
Context: Apart from lowering lipid levels, peroxisome proliferator-activated receptor (PPAR)
α activators (fibrates) produce many other favorable effects that may contribute to their …

Effects of bezafibrate on insulin sensitivity and glucose tolerance in subjects with combined hyperlipidemia

P Karhapää, M Uusitupa, E Voutilainen… - Clinical …, 1992 - Wiley Online Library
To investigate whether the lowering of triglyceride levels has beneficial effects on glucose
metabolism, we studied 13 nondiabetic men with combined hyperlipidemia (phenotype IIB) …

Effect of bezafibrate on metabolic profiles in non-insulin-dependent diabetes mellitus

K Alberti, R Jones, MF Laker, ABM Swai… - Journal of …, 1990 - journals.lww.com
Non-insuiin-dependent diabetes mellitus (NIDDM) is characterized by hyperglycemia
secondary to increased hepatic glucose output and impaired extrahepatic insulin sensitivity …

Bezafibrate reduces blood glucose in type 2 diabetes mellitus

S Ogawa, K Takeuchi, K Sugimura, M Fukuda, R Lee… - Metabolism, 2000 - Elsevier
The clinical efficacy of bezafibrate was examined with special reference to glucose
metabolism in patients with type 2 diabetes mellitus (DM2). In protocol 1, 342 patients with …

Monocyte-suppressing effect of high-dose metformin in fenofibrate-treated patients with impaired glucose tolerance

R Krysiak, A Gdula-Dymek, B Okopień - Pharmacological Reports, 2013 - Elsevier
Background Fibrates were found to reduce cytokine release and low-grade inflammation in
patients with impaired glucose tolerance. The aim of this study was to investigate whether …

Effects of bezafibrate on insulin sensitivity and insulin secretion in non-obese Japanese type 2 diabetic patients

A Taniguchi, M Fukushima, M Sakai… - Metabolism …, 2001 - metabolismjournal.com
The aim of the present study was to investigate the effect of bezafibrate on insulin sensitivity
and insulin secretion in 30 non-obese Japanese type 2 diabetic patients with …

Double‐blind Placebo‐controlled Study of the Effects of Bezafibrate on Blood Lipids, Lipoproteins, and Fibrinogen in Hyperlipidaemic Type 1 Diabetes Mellitus

PH Winocour, PN Durrington, D Bhatnagar… - Diabetic …, 1990 - Wiley Online Library
The effects of bezafibrate 400 mg day− 1 or placebo administered for 3 months, were
compared in 36 patients with stable Type 1 diabetes and hypercholesterolaemia and/or …

Effects of bezafibrate on insulin secretion and peripheral insulin sensitivity in hyperlipidemic patients with and without diabetes

G Riccardi, S Genovese, G Saldalamacchia, L Patti… - Atherosclerosis, 1989 - Elsevier
Although it has been reported that bezafibrate influences carbohydrate metabolism, this
possibility has never been properly evaluated in a controlled clinical trial. In this study we …