Methods: Fasted subjects were studied on 4 study days in random order. Subjects
consumed 50 ml of either water, sucralose (0.083% w/v), a non-sweet, glucose-polymer …

Non-nutritive sweeteners are thought to be useful replacements for caloric sweeteners in
sweet food and beverages, since the reduction in energy and carbohydrate intake may lead …

Objectives Emerging evidence shows that non-nutritive sweeteners might induce glucose
intolerance. This study aims to determine the effects of chronic exposure to sucralose on …

It has been reported that the artificial sweetener, sucralose, stimulates glucose absorption in
rodents by enhancing apical availability of the transporter GLUT2. We evaluated whether …

Background Recently, the absence of metabolic effects from nonnutritive sweeteners has
been questioned. Objective The aim of this study was to evaluate the effects of sucralose …

The incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP), play an important role in glucose homeostasis in both …

Background Non-nutritive sweeteners (NNS) are widely consumed by humans due to their
apparent innocuity, especially sucralose. However, several studies link sucralose …

The discovery of gut sweet taste receptors has led to speculations that non-nutritive
sweeteners, including sucralose, may affect glucose control. A double-blind, parallel …

Here, we tested the hypothesis that sucralose differentially affects metabolic responses to
labeled oral glucose tolerance tests (OGTTs) in participants with normal weight and obesity …

Nonnutritive sweeteners have been used to lower the energy density of foods with the
intention of affecting weight loss or weight maintenance. However, some epidemiological …