Two processes permit the urine pH and the medullary interstitial pH to remain in an “ideal
range” to minimize the risk of forming kidney stones. First, a medullary shunt for NH3 …

Pines and Mudge (1) coined the term “renal tubular acidosis”(RTA) to denote a renal tubular
disorder that causes acidosis by restricting the reduction of urinary pH and thereby the …

Acid-base balance and potassium disorders are often clinically linked. Importantly, acid-
base disorders alter potassium transport. In general, acidosis causes decreased K+ …

The formation of various types of kidney stones is strongly influenced by urinary pH. An
alkaline pH favors the crystallization of calcium-and phosphate-containing stones, whereas …

Control of potassium excretion: a Paleolithic perspective : Current Opinion in Nephrology and
Hypertension Control of potassium excretion: a Paleolithic perspective : Current Opinion in …

Abstract Background. Patients with CaHPO4 kidney stones belong to a diagnostic category
that has a high urine pH as its common feature. Our objective was to provide a new clinical …

The most common metabolic abnormality found in calcium (Ca) kidney stone formers is
idiopathic hypercalciuria (IH). Using endogenous lithium (Li) clearance, we previously …

The most common presentation of nephrolithiasis is idiopathic calcium stones in patients
without systemic disease. Most stones are primarily composed of calcium oxalate and form …

We studied six patients with renal stone disease, hypercalciuria, cystinuria and/or
hyperuricosuria, during variations in dietary Na and Cl intake. Switching between equimolar …

Excessive acid load is considered a risk factor for both Nephrolithiasis and osteoporosis.
The mechanisms by which acid confer the risk involves multiple organs, and is highly …