The host defense response critically depends on the production of leukocytes by the marrow
and the controlled delivery of these cells to relevant sites of inflammation/infection. The …

Clinical use of G-CSF can result in vascular and inflammatory complications,,,,,,. To
investigate the molecular basis of these effects, we analyzed the adherence of G-CSF …

Granulocyte colony-stimulating factor (G-CSF), a protein that stimulates the growth of new
blood cells, was isolated from human cells by Malcolm Moore and Karl Welte in 1984 [1]. It …

In this study, we have identified a unique combinatorial effect of the chemokines KC/MIP-2
and the cytokine granulocyte colony-stimulating factor (G-CSF) with respect to the rapid …

Neutrophils are released from the bone marrow in a regulated fashion to maintain
homeostatic levels in the blood and to respond to physiological stresses, including infection …

Tumor‐derived G‐CSF is a well‐known factor to aggravate disease progression in various
types of cancers. In this study, we investigated a role of G‐CSF in squamous cell carcinoma …

Microbicidal and cytocidal products of the respiratory burst and integrin adhesion molecule
expression have been studied in monocytes from patients who received rHuGM‐CSF during …

The colony-stimulating factors (CSF) are a family of glycoprotein hormones that regulate the
proliferation and maturation of hematopoietic progenitor cells. In addition to their effects on …

The granulocyte-macrophage colony-stimulating factor (GM-CSF) was initially classified as a
hematopoietic growth factor. However, unlike its close relatives macrophage CSF (M-CSF) …

GM-CSF stimulates proliferation of myeloid precursors in bone marrow and primes mature
leukocytes for enhanced functionality. We demonstrate that GM-CSF is a powerful …