scRNA-seq mixology: towards better benchmarking of single cell RNA-seq analysis methods

L Tian, X Dong, S Freytag, KA Le Cao, S Su… - BioRxiv, 2018 - biorxiv.org
Single cell RNA sequencing (scRNA-seq) technology has undergone rapid development in
recent years, bringing with it new challenges in data processing and analysis. This has led …

Benchmarking single cell RNA-sequencing analysis pipelines using mixture control experiments

L Tian, X Dong, S Freytag, KA Lê Cao, S Su… - Nature …, 2019 - nature.com
Single cell RNA-sequencing (scRNA-seq) technology has undergone rapid development in
recent years, leading to an explosion in the number of tailored data analysis methods …

[HTML][HTML] The impact of package selection and versioning on single-cell RNA-seq analysis

JM Rich, L Moses, PH Einarsson, K Jackson… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Standard single-cell RNA-sequencing analysis (scRNA-seq) workflows consist of converting
raw read data into cell-gene count matrices through sequence alignment, followed by …

Exploring the single-cell RNA-seq analysis landscape with the scRNA-tools database

L Zappia, B Phipson, A Oshlack - PLoS computational biology, 2018 - journals.plos.org
As single-cell RNA-sequencing (scRNA-seq) datasets have become more widespread the
number of tools designed to analyse these data has dramatically increased. Navigating the …

Scaling up single-cell RNA-seq data analysis with CellBridge workflow

N Nouri, AH Kurlovs, G Gaglia, E de Rinaldis… - …, 2023 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of gene expression
at the individual cell level, unraveling unprecedented insights into cellular heterogeneity …

User-friendly, scalable tools and workflows for single-cell RNA-seq analysis

P Moreno, N Huang, JR Manning, S Mohammed… - Nature …, 2021 - nature.com
To the Editor—As single-cell RNA sequencing (scRNA-seq) becomes widespread,
accessible and scalable computational pipelines for data analysis are needed. We introduce …

Shaoxia: a web-based interactive analysis platform for single cell RNA sequencing data

W Wei, X Xia, T Li, Q Chen, X Feng - BMC genomics, 2024 - Springer
Abstract Background In recent years, Single-cell RNA sequencing (scRNA-seq) is
increasingly accessible to researchers of many fields. However, interpreting its data …

[HTML][HTML] Practical bioinformatics pipelines for single-cell RNA-seq data analysis

J He, L Lin, J Chen - Biophysics Reports, 2022 - ncbi.nlm.nih.gov
Single-cell RNA sequencing (scRNA-seq) is a revolutionary tool to explore cells. With an
increasing number of scRNA-seq data analysis tools that have been developed, it is …

Single-cell RNA sequencing analysis: a step-by-step overview

S Slovin, A Carissimo, F Panariello, A Grimaldi… - RNA bioinformatics, 2021 - Springer
Thanks to innovative sample-preparation and sequencing technologies, gene expression in
individual cells can now be measured for thousands of cells in a single experiment. Since its …

Interactive single cell RNA-Seq analysis with the Single Cell Toolkit (SCTK)

DF Jenkins, T Faits, E Briars, S Carrasco Pro… - BioRxiv, 2018 - biorxiv.org
Single cell RNA-sequencing (scRNA-Seq) allows researchers to profile transcriptional
activity in individual cells. However, the complex nature of these data and variability in study …