Exosomes as novel bio-carriers for gene and drug delivery

XC Jiang, JQ Gao - International journal of pharmaceutics, 2017 - Elsevier
Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic
delivery systems. Recent studies have identified exosomes for their potential use as cell-free …

[HTML][HTML] Exosome-based drug delivery: translation from bench to clinic

HB Koh, HJ Kim, SW Kang, TH Yoo - Pharmaceutics, 2023 - mdpi.com
Exosome-based drug delivery is emerging as a promising field with the potential to
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …

Possibility of exosome-based therapeutics and challenges in production of exosomes eligible for therapeutic application

T Yamashita, Y Takahashi, Y Takakura - … and Pharmaceutical Bulletin, 2018 - jstage.jst.go.jp
Exosomes are cell-derived vesicles with a diameter 30–120 nm. Exosomes contain
endogenous proteins and nucleic acids; delivery of these molecules to exosome-recipient …

[HTML][HTML] Exosome as drug delivery system: Current advancements

V Sharma, CD Mukhopadhyay - Extracellular Vesicle, 2024 - Elsevier
Exosomes are nanovesicles released from cells due to pathophysiological events. These
nanoparticles are resistant to metabolic destruction and can transcend the blood-brain …

Drug loading techniques for exosome-based drug delivery systems

XM Xi, SJ Xia, R Lu - Die Pharmazie-An International Journal …, 2021 - ingentaconnect.com
Exosomes are bilayer membrane-coated extracellular vesicles measuring between 40 and
100 nm in diameter. As a natural carrier, exosomes have the advantages of low …

State-of-the-art exosome loading and functionalization techniques for enhanced therapeutics: a review

J Donoso-Quezada, S Ayala-Mar… - Critical reviews in …, 2020 - Taylor & Francis
Exosomes are a subpopulation of cell membrane-derived vesicles which play an essential
role in cellular communication. In recent years, several studies have exploited the natural …

Exosome: a significant nano-scale drug delivery carrier

H Peng, W Ji, R Zhao, J Yang, Z Lu, Y Li… - Journal of Materials …, 2020 - pubs.rsc.org
In recent years, due to the limitations of the nature of therapeutic agents, many synthetic
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …

[HTML][HTML] Engineering exosomes as refined biological nanoplatforms for drug delivery

X Luan, K Sansanaphongpricha, I Myers… - Acta Pharmacologica …, 2017 - nature.com
Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important
mediators of long distance intercellular communication and are involved in a diverse range …

Pharmacokinetics of exosomes—an important factor for elucidating the biological roles of exosomes and for the development of exosome-based therapeutics

M Morishita, Y Takahashi, M Nishikawa… - Journal of …, 2017 - Elsevier
Exosomes are small membrane vesicles containing lipids, proteins, and nucleic acids.
Recently, researchers have uncovered that exosomes are involved in various biological …

Exosomes as a drug delivery system in cancer therapy: potential and challenges

G Kibria, EK Ramos, Y Wan, DR Gius… - Molecular …, 2018 - ACS Publications
Exosomes play a pivotal role in mediating intercellular communications and package
delivery. They have recently been discovered to serve as diagnostic biomarkers as well as a …