[HTML][HTML] Manufacturing therapeutic exosomes: from bench to industry

SH Ahn, SW Ryu, H Choi, S You, J Park, C Choi - Molecules and cells, 2022 - Elsevier
Exosome, a type of nanoparticles also known as small extracellular vesicles are gaining
attention as novel therapeutics for various diseases because of their ability to deliver genetic …

Current knowledge on exosome biogenesis, cargo-sorting mechanism and therapeutic implications

S Xie, Q Zhang, L Jiang - Membranes, 2022 - mdpi.com
Extracellular vesicles (EVs) are nanoscale membrane vesicles released by donor cells that
can be taken up by recipient cells. The study of EVs has the potential to identify unknown …

[HTML][HTML] Exosomes as drug carriers for cancer therapy and challenges regarding exosome uptake

X Zhao, D Wu, X Ma, J Wang, W Hou… - Biomedicine & …, 2020 - Elsevier
With the development of biomedicine, exosomes are rapidly developing as a new therapy
for tumors. As biological carriers, exosomes possess biological activity and can transport …

Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications

MN Huda, M Nafiujjaman, IG Deaguero… - ACS biomaterials …, 2021 - ACS Publications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …

Exosome-based drug delivery systems in cancer therapy

T Wang, Y Fu, S Sun, C Huang, Y Yi, J Wang… - Chinese Chemical …, 2023 - Elsevier
Exosome, which is a kind of extracellular vesicles with size around 40-160 nm, plays an
important role in cell-to-cell communication in multiple diseases. Especially in tumor …

Engineered exosomes: a promising drug delivery strategy for brain diseases

Y Jiang, F Wang, K Wang, Y Zhong… - Current Medicinal …, 2022 - benthamdirect.com
Exosomes are a heterogeneous group of nano-sized natural membrane vesicles released
from various cells and exist in body fluids. Different from the previous understanding of the …

A novel strategy to increase the yield of exosomes (extracellular vesicles) for an expansion of basic research

SE Emam, H Ando, ASA Lila, T Shimizu… - Biological and …, 2018 - jstage.jst.go.jp
Exosomes are tiny extracellular vesicles that are usually harvested in small quantities. Such
small yield has been an obstacle for the expansion of the basic research regarding exosome …

[HTML][HTML] Exosome theranostics: biology and translational medicine

C He, S Zheng, Y Luo, B Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …

Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment

A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), is the umbrella term used for different types of vesicles
produced by the cells, among which exosomes form the largest group. Exosomes perform …

Exosome: a new player in translational nanomedicine

H Aheget, M Tristán-Manzano, L Mazini… - Journal of Clinical …, 2020 - mdpi.com
Exosomes are extracellular vesicles released by the vast majority of cell types both in vivo
and ex vivo, upon the fusion of multivesicular bodies (MVBs) with the cellular plasma …