Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation

T Yamashita, Y Takahashi, M Nishikawa… - European Journal of …, 2016 - Elsevier
Exosomes, which are expected to be delivery systems for biomolecules such as nucleic
acids, are collected by several methods. However, the effect of exosome isolation methods …

Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance

S Salunkhe, M Basak, D Chitkara, A Mittal - Journal of Controlled …, 2020 - Elsevier
Exosomes are natural nanovesicles excreted by many cells for intercellular communication
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …

Post isolation modification of exosomes for nanomedicine applications

JL Hood - Nanomedicine, 2016 - Taylor & Francis
Exosomes are extracellular nanovesicles. They innately possess ideal structural and
biocompatible nanocarrier properties. Exosome components can be engineered at the …

Exosomes from different cells: Characteristics, modifications, and therapeutic applications

M Li, S Li, C Du, Y Zhang, Y Li, L Chu, X Han… - European Journal of …, 2020 - Elsevier
Exosomes are cystic vesicles secreted by living cells with a phospholipid bilayer membrane.
Importantly, these vesicles could serve to carry lipids, proteins, genetic materials, and …

Improvement, scaling-up, and downstream analysis of exosome production

D Jafari, S Malih, M Eini, R Jafari… - Critical reviews in …, 2020 - Taylor & Francis
Exosomes are the most researched extracellular vesicles. In many biological, physiological,
and pathological studies, they have been identified as suitable candidates for treatment and …

Emerging applications of exosomes in cancer therapeutics and diagnostics

S Inamdar, R Nitiyanandan… - … & translational medicine, 2017 - Wiley Online Library
Exosomes are nanoscale extracellular vesicles that are shed from different cells in the body.
Exosomes encapsulate several biomolecules including lipids, proteins, and nucleic acids …

Exosome-like nanovectors for drug delivery in cancer

N Arrighetti, C Corbo, M Evangelopoulos… - Current medicinal …, 2019 - ingentaconnect.com
Cancer treatment still represents a formidable challenge, despite substantial advancements
in available therapies being made over the past decade. One major issue is poor …

[HTML][HTML] Exosomes and other extracellular vesicles with high therapeutic potential: their applications in oncology, neurology, and dermatology

U Szwedowicz, Z Łapińska, A Gajewska-Naryniecka… - Molecules, 2022 - mdpi.com
Until thirty years ago, it was believed that extracellular vesicles (EVs) were used to remove
unnecessary compounds from the cell. Today, we know about their enormous potential in …

[HTML][HTML] A review on exosomes application in clinical trials: perspective, questions, and challenges

J Rezaie, M Feghhi, T Etemadi - Cell Communication and Signaling, 2022 - Springer
Background Exosomes are progressively known as significant mediators of cell-to-cell
communication. They convey active biomolecules to target cells and have vital functions in …

[HTML][HTML] Recent advancements in the loading and modification of therapeutic exosomes

M Xu, Q Yang, X Sun, Y Wang - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Exosomes have a rapid development of bio-nanoparticles for drug delivery and confluent
advances in next-generation diagnostics, monitoring the progression of several diseases …