A genetic family study was undertaken by photofluorography of the first, second, and third
degree relatives of 116 index patients with adolescent idiopathic scoliosis (AIS). The index …

Families of 241 patients among 913 cases of idiopathic scoliosis were surveyed. The data
suggest two possible modes of inheritance: either an autosomal dominant inheritance with …

Materials and Methods The study population consisted of 1378 patients with idiopathic
scoliosis, seen in the Hospital For Special Surgery Scoliosis Clinic, New York City, from …

Segregation analysis using a model with age and gender effects was applied to 101
pedigrees ascertained through a proband with idiopathic scoliosis. The transmission …

A Genetic Survey of Idiopathic Scoliosis in Page 1 A Genetic Survey of Idiopathic Scoliosis
in Boston, Massachusetts BY EDWARD J. RISEBOROUGH, MD*, BOSTON …

A heritability study of 69 extended Utah families with a history of adolescent idiopathic
scoliosis (AIS) indicates that AIS is a polygenic, multifactorial condition. Each family reported …

1. Idiopathic scoliosis is a familial condition. 2. The findings suggest either dominant or
multiple gene inheritance, but a larger series is needed before a firm conclusion can be …

Scoliosis Clinic and the Department of Human Genetics, Hadassah University Hospital,
Jerusalem Scoliosis appeared in fifteen members of a family in three generations. The eight …

SCOLIOSIS is defined as a lateral curvature of the spine and may be non-structural or
structural. Postural and compensatory scoliosis (resulting, for example, from a short leg) are …

Purpose: The role of genetic factors in the development of Adolescent Idiopathic Scoliosis
(AIS) has been well documented; however, reports of the specific mode of genetic …