Weight gain associated with integrase stand transfer inhibitor use in women

AM Kerchberger, AN Sheth, CD Angert… - Clinical infectious …, 2020 - academic.oup.com
Background Integrase strand-transfer inhibitor (INSTI)-based antiretroviral therapy (ART) is
recommended for human immunodeficiency virus (HIV) management. Although studies …

Risk factors for weight gain following switch to integrase inhibitor–based antiretroviral therapy

JE Lake, K Wu, SH Bares, P Debroy… - Clinical Infectious …, 2020 - academic.oup.com
Background Treatment initiation with integrase strand transfer inhibitors (INSTIs) has been
associated with excess weight gain. Whether similar gains are seen after switch to INSTIs …

Metabolic changes associated with the use of integrase strand transfer inhibitors among virally controlled women

NA Summers, CD Lahiri, CD Angert… - JAIDS Journal of …, 2020 - journals.lww.com
Background: Integrase strand transfer inhibitors (INSTIs) have been associated with weight
gain among women living with HIV. We aimed to investigate the association between INSTIs …

No overall change in the rate of weight gain after switching to an integrase-inhibitor in virologically suppressed adults with HIV

JE Burns, OT Stirrup, D Dunn, I Runcie-Unger… - Aids, 2020 - journals.lww.com
Objective: Excessive weight gain has been reported with integrase strand transfer inhibitors
(INSTIs). We evaluated weight changes in virologically suppressed adults with HIV who …

Integrase strand transfer inhibitors are associated with incident diabetes mellitus in people with human immunodeficiency virus

JA O'Halloran, J Sahrmann… - Clinical Infectious …, 2022 - academic.oup.com
Background Integrase strand transfer inhibitors (INSTIs) are associated with weight gain in
people with HIV (PWH). Less is known about the risk of other metabolic outcomes such as …

Effects of different integrase strand transfer inhibitors on body weight in patients with HIV/AIDS: a network meta-analysis

R Bai, S Lv, H Wu, L Dai - BMC infectious diseases, 2022 - Springer
Background Global antiretroviral therapy has entered a new era. Integrase strand transfer
inhibitor (INSTI) has become the first choice in acquired immunodeficiency syndrome (AIDS) …

Relationship between weight gain and insulin resistance in people living with HIV switching to integrase strand transfer inhibitors-based regimens

J Milic, S Renzetti, D Ferrari, S Barbieri, M Menozzi… - Aids, 2022 - journals.lww.com
Objective: The primary objective was to explore weight and BMI changes in people with HIV
(PWH) undergoing integrase strand transfer inhibitors (INSTI)-based regimens (vs. non …

Weight gain among treatment‐naïve persons with HIV starting integrase inhibitors compared to non‐nucleoside reverse transcriptase inhibitors or protease inhibitors …

K Bourgi, CA Jenkins, PF Rebeiro… - Journal of the …, 2020 - Wiley Online Library
Introduction Weight gain following antiretroviral therapy (ART) initiation is common,
potentially predisposing some persons with HIV (PWH) to cardio‐metabolic disease. We …

Efavirenz pharmacogenetics and weight gain following switch to integrase inhibitor–containing regimens

MA Leonard, Z Cindi, Y Bradford… - Clinical Infectious …, 2021 - academic.oup.com
Background Unwanted weight gain affects some people living with human
immunodeficiency virus (HIV) who are prescribed integrase strand transfer inhibitors …

Weight gain and integrase inhibitors

AR Eckard, GA McComsey - Current opinion in infectious diseases, 2020 - journals.lww.com
Although INSTI-based regimens are highly efficacious for viral suppression, they appear to
cause more weight gain and treatment emergent obesity than non-INSTI-based regimens …