Modulation of angiogenesis for disease therapy was proposed nearly 40years ago and
today various protein and chemical molecules are available for the treatment of human …

Abstract Angiopoietin-like 2 (ANGPTL2) has been reported to induce sprouting
angiogenesis; however, its role in vasculogenesis, the de novo lumenization of endothelial …

Critical limb ischemia (CLI) is the advanced stage of peripheral artery disease spectrum and
is defined by limb pain or impending limb loss because of compromised blood flow to the …

Since the start of 2021, Dr. Joyce Bischoff has stepped down as Co-Editor in Chief of
Angiogenesis [1]. Our new Co-Editor in Chief is Dr. Andrew C. Dudley from the University of …

Deregulated angiogenesis has been identified as a key contributor in a number of
pathological conditions including cancer. It is a complex process, which involves highly …

This review of angiogenesis aims to describe (a) stimuli that either elicit or antagonize
angiogenesis,(b) the response of the vasculature to angiogenic or antiangiogenic stimuli, ie …

Atherosclerotic disease of the arteries is a major cause of coronary artery disease,
peripheral vascular disease and stroke. Some patients are however not candidate for the …

Blood and vascular disorders underlie a plethora of pathologic conditions and are the single
most frequent cause of human disease. Ischemia, involving restricted blood flow to tissues is …

Pathological angiogenesis is a hallmark of various ischemic diseases (insufficient vessel
growth) but also of cancer and metastasis, inflammatory diseases, blindness, psoriasis or …

Peripheral arterial disease (PAD) remains a major cause of morbidity. Despite advances in
revascularisation procedures and medical treatment, limb salvage and relief of pain are still …