National epidemiology of initial and recurrent Clostridium difficile infection in the Veterans Health Administration from 2003 to 2014

KR Reveles, KA Lawson, EM Mortensen, MJV Pugh… - PLoS …, 2017 - journals.plos.org
Introduction Prior studies demonstrated marked increases in Clostridium difficile infection
(CDI) in the United States (US) in recent years. The objective of this study was to describe …

The effect of antibiotic therapy for Clostridioides difficile infection on mortality and other patient-relevant outcomes: a systematic review and meta-analysis

Y Stabholz, M Paul - Clinical Microbiology and Infection, 2024 - Elsevier
Background Current practice guidelines favour fidaxomicin over vancomycin and exclude
metronidazole from the recommended standard regimen for Clostridioides difficile infection …

Cost-effectiveness of Treatment Regimens for Clostridioides difficile Infection: An Evaluation of the 2018 Infectious Diseases Society of America Guidelines

R Rajasingham, EA Enns, A Khoruts… - Clinical infectious …, 2020 - academic.oup.com
Abstract Background In 2018, the Infectious Diseases Society of America (IDSA) published
guidelines for diagnosis and treatment of Clostridioides (formerly Clostridium) difficile …

Risk factors for recurrent Clostridium difficile infection (CDI) hospitalization among hospitalized patients with an initial CDI episode: a retrospective cohort study

MD Zilberberg, K Reske, M Olsen, Y Yan… - BMC Infectious …, 2014 - Springer
Abstract Background Recurrent Clostridium difficile infection (rCDI) is observed in up to 25%
of patients with an initial CDI episode (iCDI). We assessed risk factors for rCDI among …

National age group trends in Clostridium difficile infection incidence and health outcomes in United States Community Hospitals

A Pechal, K Lin, S Allen, K Reveles - BMC infectious diseases, 2016 - Springer
Background Prior studies have demonstrated an increase in Clostridium difficile infection
(CDI) incidence in the United States (US) in recent years, but trends among different age …

The burden of clostridium difficile infection: estimates of the incidence of CDI from US Administrative databases

MA Olsen, Y Young-Xu, D Stwalley, CP Kelly… - BMC infectious …, 2016 - Springer
Background Many administrative data sources are available to study the epidemiology of
infectious diseases, including Clostridium difficile infection (CDI), but few publications have …

Cost-effectiveness of three different strategies for the treatment of first recurrent Clostridium difficile infection diagnosed in a community setting

SW Lam, EA Neuner, TG Fraser, D Delgado… - Infection Control & …, 2018 - cambridge.org
ObjectiveA significant portion of patients with Clostridium difficile infections (CDI) experience
recurrence, and there is little consensus on its treatment. With the availability of newer …

Attributable burden of hospital-onset Clostridium difficile infection: a propensity score matching study

YP Tabak, MD Zilberberg, RS Johannes… - Infection Control & …, 2013 - cambridge.org
Objective. To determine the attributable in-hospital mortality, length of stay (LOS), and cost of
hospital-onset Clostridium difficile infection (HO-CDI). Design. Propensity score matching …

Short-and long-term attributable costs of Clostridium difficile-associated disease in nonsurgical inpatients

ER Dubberke, KA Reske, MA Olsen… - Clinical Infectious …, 2008 - academic.oup.com
Abstract Background. The incidence of Clostridium difficile–associated disease (CDAD) is
increasing. There are few data on the short-term and long-term attributable costs of CDAD …

A population-based matched cohort study examining the mortality and costs of patients with community-onset Clostridium difficile infection identified using emergency …

N Nanwa, B Sander, M Krahn, N Daneman, H Lu… - PloS one, 2017 - journals.plos.org
Few studies have evaluated the mortality or quantified the economic burden of community-
onset Clostridium difficile infection (CDI). We estimated the attributable mortality and costs of …