Radiotherapy in the management of pediatric and adult osteosarcomas: a multi-institutional cohort analysis

MJ Spałek, J Poleszczuk, AM Czarnecka… - Cells, 2021 - mdpi.com
Background: Due to the rarity of osteosarcoma and limited indications for radiotherapy (RT),
data on RT for this tumor are scarce. This study aimed to investigate the utilization of RT for …

Multimodality treatment of osteosarcoma: radiation in a high‐risk cohort

A Mahajan, SY Woo, DG Kornguth… - Pediatric blood & …, 2008 - Wiley Online Library
Purpose Chemotherapy during radiation and/or bone‐seeking radioisotope therapy (153‐
samarium; 1 mCi/kg) during radiation may improve osteosarcoma cancer control. Patients …

Curative‐intent radiotherapy for pediatric osteosarcoma: The St. Jude experience

CL Tinkle, J Lu, Y Han, Y Li… - Pediatric blood & …, 2019 - Wiley Online Library
Background Radiation therapy (RT) confers local tumor control and survival advantages in
some patients with osteosarcoma, yet pediatric and adolescent and young adult (AYA) …

Outcomes for pediatric patients with osteosarcoma treated with palliative radiotherapy

EL Chen, CH Yoo, PM Gutkin, DJ Merriott… - Pediatric Blood & …, 2020 - Wiley Online Library
Background Few studies have addressed the efficacy of palliative radiotherapy (RT) for
pediatric osteosarcoma (OS), a disease generally considered to be radioresistant. We …

Non-randomized therapy trial to determine the safety and efficacy of heavy ion radiotherapy in patients with non-resectable osteosarcoma

C Blattmann, S Oertel, D Schulz-Ertner, S Rieken… - BMC cancer, 2010 - Springer
Background Osteosarcoma is the most common primary malignant bone tumor in children
and adolescents. For effective treatment, local control of the tumor is absolutely critical …

Radiation-induced osteosarcomas in the pediatric population

M Koshy, AC Paulino, WY Mai, BS Teh - International Journal of Radiation …, 2005 - Elsevier
Purpose: Radiation-induced osteosarcomas (R-OS) have historically been high-grade,
locally invasive tumors with a poor prognosis. The purpose of this study was to perform a …

Outcome of radiation-related osteosarcoma after treatment of childhood and adolescent cancer: a study of 23 cases

MD Tabone, P Terrier, H Pacquement… - Journal of clinical …, 1999 - ascopubs.org
PURPOSE: We analyzed the clinical features and outcome of patients with radiation-
associated osteosarcoma treated during the era of contemporary chemotherapy. PATIENTS …

The role of radiotherapy in oseosarcoma

R Schwarz, O Bruland, A Cassoni… - Pediatric and …, 2010 - Springer
A survey of the literature shows that the experience with radiotherapy (RT) in the local
treatment of osteosarcoma (OS) is limited. This is due to various reasons: OS is a rare tumor …

Radiotherapy in the treatment of primary osteosarcoma–a single center experience

S Oertel, C Blattmann, S Rieken, A Jensen… - Tumori …, 2010 - journals.sagepub.com
Purpose To analyze our experiences concerning radiation treatment in patients with
osteosarcoma. Materials and methods Since 1981, 40 patients with osteosarcoma have …

Osteosarcoma

BR Eaton, R Schwarz, R Vatner, B Yeh… - Pediatric blood & …, 2021 - Wiley Online Library
Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This
paper reviews the general management and standard radiotherapy guidelines for …