[HTML][HTML] Serine-scanning mutagenesis studies of the C-terminal heptad repeats in the SARS coronavirus S glycoprotein highlight the important role of the short helical …
KE Follis, J York, JH Nunberg - Virology, 2005 - Elsevier
The fusion subunit of the SARS-CoV S glycoprotein contains two regions of hydrophobic
heptad-repeat amino acid sequences that have been shown in biophysical studies to form a …
heptad-repeat amino acid sequences that have been shown in biophysical studies to form a …
[HTML][HTML] Structures and polymorphic interactions of two heptad-repeat regions of the SARS virus S2 protein
Y Deng, J Liu, Q Zheng, W Yong, M Lu - Structure, 2006 - cell.com
Entry of SARS coronavirus into its target cell requires large-scale structural transitions in the
viral spike (S) glycoprotein in order to induce fusion of the virus and cell membranes. Here …
viral spike (S) glycoprotein in order to induce fusion of the virus and cell membranes. Here …
[HTML][HTML] Mutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein: refinement of the requirements for SARS coronavirus cell entry
J Corver, R Broer, P van Kasteren, W Spaan - Virology journal, 2009 - Springer
Background The spike protein (S) of SARS Coronavirus (SARS-CoV) mediates entry of the
virus into target cells, including receptor binding and membrane fusion. Close to or in the …
virus into target cells, including receptor binding and membrane fusion. Close to or in the …
[HTML][HTML] Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion
CM Petit, JM Melancon, VN Chouljenko, R Colgrove… - Virology, 2005 - Elsevier
The SARS-coronavirus (SARS-CoV) is the etiological agent of severe acute respiratory
syndrome (SARS). The SARS-CoV spike (S) glycoprotein mediates membrane fusion events …
syndrome (SARS). The SARS-CoV spike (S) glycoprotein mediates membrane fusion events …
[HTML][HTML] Substitution at aspartic acid 1128 in the SARS coronavirus spike glycoprotein mediates escape from a S2 domain-targeting neutralizing monoclonal antibody
OW Ng, CT Keng, CSW Leung, JSM Peiris, LLM Poon… - PLoS …, 2014 - journals.plos.org
The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is the etiological agent
for the infectious disease, SARS, which first emerged 10 years ago. SARS-CoV is a zoonotic …
for the infectious disease, SARS, which first emerged 10 years ago. SARS-CoV is a zoonotic …
[HTML][HTML] Palmitoylation of the cysteine-rich endodomain of the SARS–coronavirus spike glycoprotein is important for spike-mediated cell fusion
The SARS–coronavirus (SARS–CoV) is the etiological agent of the severe acute respiratory
syndrome (SARS). The SARS–CoV spike (S) glycoprotein mediates membrane fusion …
syndrome (SARS). The SARS–CoV spike (S) glycoprotein mediates membrane fusion …
GxxxG motif of severe acute respiratory syndrome coronavirus spike glycoprotein transmembrane domain is not involved in trimerization and is not important for entry
J Corver, R Broer, P van Kasteren, W Spaan - Journal of virology, 2007 - Am Soc Microbiol
Recently, a paper was published in which it was proposed that the GxxxG motif of the severe
acute respiratory syndrome (SARS) coronavirus spike (S) protein transmembrane domain …
acute respiratory syndrome (SARS) coronavirus spike (S) protein transmembrane domain …
[HTML][HTML] Structural characterization of the SARS-coronavirus spike S fusion protein core
B Tripet, MW Howard, M Jobling, RK Holmes… - Journal of Biological …, 2004 - ASBMB
The spike (S) glycoprotein of coronaviruses mediates viral entry into host cells. It is a type 1
viral fusion protein that characteristically contains two heptad repeat regions, denoted HR-N …
viral fusion protein that characteristically contains two heptad repeat regions, denoted HR-N …
[HTML][HTML] Conformational reorganization of the SARS coronavirus spike following receptor binding: implications for membrane fusion
DR Beniac, SL deVarennes, A Andonov, R He… - PloS one, 2007 - journals.plos.org
The SARS coronavirus (SARS-CoV) spike is the largest known viral spike molecule, and
shares a similar function with all class 1 viral fusion proteins. Previous structural studies of …
shares a similar function with all class 1 viral fusion proteins. Previous structural studies of …
[HTML][HTML] SARS-coronavirus spike S2 domain flanked by cysteine residues C822 and C833 is important for activation of membrane fusion
IG Madu, S Belouzard, GR Whittaker - Virology, 2009 - Elsevier
The S2 domain of the coronavirus spike (S) protein is known to be responsible for mediating
membrane fusion. In addition to a well-recognized cleavage site at the S1–S2 boundary, a …
membrane fusion. In addition to a well-recognized cleavage site at the S1–S2 boundary, a …