Production of mice using iPS cells and tetraploid complementation
Induced pluripotent stem cells (iPSCs) are considered to be an attractive alternative to
embryonic stem cells (ESCs) and may provide great potential for clinical applications in …
embryonic stem cells (ESCs) and may provide great potential for clinical applications in …
Pluripotency of induced pluripotent stem cells
L Kang, S Gao - Journal of animal science and biotechnology, 2012 - Springer
Recent studies have demonstrated that differentiated somatic cells from various mammalian
species can be reprogrammed into induced pluripotent stem (iPS) cells by the ectopic …
species can be reprogrammed into induced pluripotent stem (iPS) cells by the ectopic …
iPS cells produce viable mice through tetraploid complementation
X Zhao, W Li, Z Lv, L Liu, M Tong, T Hai, J Hao, C Guo… - nature, 2009 - nature.com
Since the initial description of induced pluripotent stem (iPS) cells created by forced
expression of four transcription factors in mouse fibroblasts, the technique has been used to …
expression of four transcription factors in mouse fibroblasts, the technique has been used to …
Viable fertile mice generated from fully pluripotent iPS cells derived from adult somatic cells
Previous studies demonstrated that induced pluripotent stem (iPS) cells could produce
viable mice through tetraploid complementation, which was thought to be the most stringent …
viable mice through tetraploid complementation, which was thought to be the most stringent …
Generation of mice derived from induced pluripotent stem cells
The production of induced pluripotent stem cells (iPSCs) from somatic cells provides a
means to create valuable tools for basic research and may also produce a source of patient …
means to create valuable tools for basic research and may also produce a source of patient …
Generation of mouse and human induced pluripotent stem cells (iPSC) from primary somatic cells
IM Lorenzo, A Fleischer, D Bachiller - Stem Cell Reviews and Reports, 2013 - Springer
Cellular reprogramming consists of the conversion of differentiated cells into pluripotent
cells; the so-called induced Pluripotent Stem Cells. iPSC are amenable to in vitro …
cells; the so-called induced Pluripotent Stem Cells. iPSC are amenable to in vitro …
Generation of human-induced pluripotent stem cells (hiPSCs) using episomal vectors on defined Essential 8™ Medium conditions
A Fontes, CC MacArthur, PT Lieu… - Pluripotent Stem Cells …, 2013 - Springer
Human-induced pluripotent stem cells (iPSCs) are an important potential source of cells for
regenerative medicine due to their inherent ability to differentiate into all cell types of the …
regenerative medicine due to their inherent ability to differentiate into all cell types of the …
Ten years of induced pluripotency: from basic mechanisms to therapeutic applications
P Karagiannis, K Eto - 2016 - journals.biologists.com
Ten years ago, the discovery that mature somatic cells could be reprogrammed into induced
pluripotent stem cells (iPSCs) redefined the stem cell field and brought about a wealth of …
pluripotent stem cells (iPSCs) redefined the stem cell field and brought about a wealth of …
Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis
Ever since the creation of induced pluripotent cells (iPSCs) from adult somatic cells by the
ectopic expression of defined transcription factors [1, 2], whether iPS cells are equivalent to …
ectopic expression of defined transcription factors [1, 2], whether iPS cells are equivalent to …
Nascent induced pluripotent stem cells efficiently generate entirely iPSC-derived mice while expressing differentiation-associated genes
The ability of induced pluripotent stem cells (iPSCs) to differentiate into all adult cell types
makes them attractive for research and regenerative medicine; however, it remains unknown …
makes them attractive for research and regenerative medicine; however, it remains unknown …