Production of mice using iPS cells and tetraploid complementation

XY Zhao, Z Lv, W Li, F Zeng, Q Zhou - Nature Protocols, 2010 - nature.com
Induced pluripotent stem cells (iPSCs) are considered to be an attractive alternative to
embryonic stem cells (ESCs) and may provide great potential for clinical applications in …

Pluripotency of induced pluripotent stem cells

L Kang, S Gao - Journal of animal science and biotechnology, 2012 - Springer
Recent studies have demonstrated that differentiated somatic cells from various mammalian
species can be reprogrammed into induced pluripotent stem (iPS) cells by the ectopic …

iPS cells produce viable mice through tetraploid complementation

X Zhao, W Li, Z Lv, L Liu, M Tong, T Hai, J Hao, C Guo… - nature, 2009 - nature.com
Since the initial description of induced pluripotent stem (iPS) cells created by forced
expression of four transcription factors in mouse fibroblasts, the technique has been used to …

Viable fertile mice generated from fully pluripotent iPS cells derived from adult somatic cells

X Zhao, W Li, Z Lv, L Liu, M Tong, T Hai, J Hao… - Stem Cell Reviews and …, 2010 - Springer
Previous studies demonstrated that induced pluripotent stem (iPS) cells could produce
viable mice through tetraploid complementation, which was thought to be the most stringent …

Generation of mice derived from induced pluripotent stem cells

MJ Boland, JL Hazen, KL Nazor, AR Rodriguez… - JoVE (Journal of …, 2012 - jove.com
The production of induced pluripotent stem cells (iPSCs) from somatic cells provides a
means to create valuable tools for basic research and may also produce a source of patient …

Generation of mouse and human induced pluripotent stem cells (iPSC) from primary somatic cells

IM Lorenzo, A Fleischer, D Bachiller - Stem Cell Reviews and Reports, 2013 - Springer
Cellular reprogramming consists of the conversion of differentiated cells into pluripotent
cells; the so-called induced Pluripotent Stem Cells. iPSC are amenable to in vitro …

Generation of human-induced pluripotent stem cells (hiPSCs) using episomal vectors on defined Essential 8™ Medium conditions

A Fontes, CC MacArthur, PT Lieu… - Pluripotent Stem Cells …, 2013 - Springer
Human-induced pluripotent stem cells (iPSCs) are an important potential source of cells for
regenerative medicine due to their inherent ability to differentiate into all cell types of the …

Ten years of induced pluripotency: from basic mechanisms to therapeutic applications

P Karagiannis, K Eto - 2016 - journals.biologists.com
Ten years ago, the discovery that mature somatic cells could be reprogrammed into induced
pluripotent stem cells (iPSCs) redefined the stem cell field and brought about a wealth of …

Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis

M Tong, Z Lv, L Liu, H Zhu, QY Zheng, XY Zhao, W Li… - Cell research, 2011 - nature.com
Ever since the creation of induced pluripotent cells (iPSCs) from adult somatic cells by the
ectopic expression of defined transcription factors [1, 2], whether iPS cells are equivalent to …

Nascent induced pluripotent stem cells efficiently generate entirely iPSC-derived mice while expressing differentiation-associated genes

B Amlani, Y Liu, T Chen, LS Ee, P Lopez, A Heguy… - Cell reports, 2018 - cell.com
The ability of induced pluripotent stem cells (iPSCs) to differentiate into all adult cell types
makes them attractive for research and regenerative medicine; however, it remains unknown …