The family of nitric oxide synthases (NOS) has significant importance in various
physiological mechanisms and is also involved in many pathological processes. Three NOS …

Nitric oxide (NO) plays an important and diverse signalling role in the cardiovascular system,
contributing to the regulation of vascular tone, endothelial function, myocardial function …

Hypertension is a prevalent condition worldwide and is the key risk factor for fatal
cardiovascular complications, such as stroke, sudden cardiac death and heart failure …

Vascular blood flow and its distribution among different vascular beds are regulated by
changes in microvascular tone. Nitric oxide (NO) plays a key role in the local paracrine …

This review describes and summarizes the role of neuronal nitric oxide synthase (nNOS) on
the central nervous system, particularly on brain regions such as the ventrolateral medulla …

Nitric oxide (NO) has multiple important actions that contribute to the maintenance of
vascular homeostasis. NO is synthesized by three different isoforms of NO synthase (NOS) …

Nitric oxide (NO) is an important vasodilator produced by vascular endothelium. Its
enzymatic formation is derived from three different synthases: neuronal (nNOS), endothelial …

Nitric oxide (NO) is an intra‐and extracellular messenger that mediates diverse signaling
pathways in target cells and is known to play an important role in many physiological …

Nitric oxide (NO) has multiple important actions that contribute to the maintenance of
vascular homeostasis. NO is synthesized by three different isoforms of NO synthase (NOS) …

In 1980, Furchgott and Zawadzki demonstrated that the relaxation of vascular smooth
muscle cells in response to acetylcholine is dependent on the anatomical integrity of the …