The pathogen control evolutionary hypothesis (PCH) of aging was critically analyzed by
Criscuolo et al.[1]. According to PCH, a shorter lifespan might have evolved to eliminate …

Lidsky and Andino claim the pathogen control hypothesis (PCH) has more explanatory
power than current theories on the evolution of ageing [1]. The PCH, based on kin selection …

Aging is often attributed to the detrimental side effects of beneficial traits but not a
programmed adaptive process. Alternatively, the pathogen control hypothesis posits that …

Here we show that pathogen-mediated selection can influence the evolution of host
longevity. Greater longevity can impair the fitness of host organisms subject to pathogen …

Species-specific limits to lifespan (lifespan setpoint) determine the life expectancy of any
given organism. Whether limiting lifespan provides an evolutionary benefit or is the result of …

Aging has the hallmarks of an evolved adaptation. It is controlled by genes that have been
conserved over vast evolutionary distances, and most organisms are able to forestall aging …

Reproduction, mortality, and immune function often change with age but do not invariably
deteriorate. Across the tree of life, there is extensive variation in age-specific performance …

Classical life-history theory predicts that acute, immunizing pathogens should maximize
between-host transmission. When such pathogens induce violent epidemic outbreaks …

Host–pathogen associations continue to generate some of the most important applied
problems in population biology. In addition, as foreshadowed in Chapter 5 of this volume …

While most evolutionary studies of host-pathogen dynamics consider pathogen evolution
alone or host-pathogen coevolution, there is evidence that hosts can evolve more rapidly …