Background: 3, 4-methylenedioxymethamphetamine (MDMA) is a chemical derivative of
amphetamine that can induce learning and memory impairment. Due to the effect of …

Ecstasy is a widely abused psychoactive recreational drug that is known to induce
neuroplastic effects. The molecular basis of addiction remains poorly understood, but …

Materials and Methods: In this experimental study, 40 male Wistar rats were used. The
animals were divided into five groups (n= 8) including control/saline group (receiving saline …

Objective (s): Chronic methamphetamine (METH) abuse is recognized as an important risk
factor for cognitive impairment. A plant-based isoquinoline alkaloid, Berberine hydrochloride …

Background: Alzheimer's disease (AD) is an age-related neurodegenerative disorder.
Evidence from neuropathological studies indicates that the levels of neurotrophins brain …

Methylenedioxymethamphetamine (MDMA or “Ecstasy”) is a psychoactive and
hallucinogenic drug of abuse. MDMA has been shown to produce neurotoxicity both in …

Objective: Pentylenetetrazole (p TZ)-induced seizures affect the serum brain-derived
neurotropic factor (BDNF) levels and also cognition in rats. In this study, effect of acute …

Materials and Methods: 70 female Sperag Dawley rats were randomly divided into seven
groups including: 1. control, 2. Sham, 3. littium chlorid [d1] e 20, 4. littium chloride 40, 5 …

Materials and Methods: We performed a chronic electrical stress model on 20 male Sprague
Dawley rats (2 months-old, 180–200 g). Rats were divided into four groups: normal control …

Results: The results of this study showed that, 8 weeks of aerobic training and intake of
omega-3, had no significant effect on the BDNF level in the hippocampus of Alzheimer …