Risk stratification for survival and leukemic transformation in essential thrombocythemia: a single institutional study of 605 patients

N Gangat, AP Wolanskyj, RF McClure, CY Li… - Leukemia, 2007 - nature.com
Unlike the case with thrombosis, prognostic models for survival and leukemic transformation
(LT) in essential thrombocythemia (ET) are not available. Among 605 patients with ET seen …

Prognostic factors for thrombosis, myelofibrosis, and leukemia in essential thrombocythemia: a study of 605 patients

F Passamonti, E Rumi, L Arcaini, E Boveri… - …, 2008 - haematologica.org
Background Essential thrombocythemia is a chronic myeloproliferative disorder; patients
with this disorder have a propensity to develop thrombosis, myelofibrosis, and leukemia …

Thrombosis-free survival and life expectancy in 187 consecutive patients with essential thrombocythemia

M Bazzan, G Tamponi, P Schinco, A Vaccarino… - Annals of …, 1999 - Springer
A total of 187 consecutive patients with essential thrombocythemia (ET) were diagnosed and
followed by our Hematology Department in the period October 1980–November 1994. The …

Impact of leukocytosis on thrombotic risk and survival in 532 patients with essential thrombocythemia: a retrospective study

F Palandri, N Polverelli, L Catani, E Ottaviani… - Annals of …, 2011 - Springer
Established risk factors for thrombosis in essential thrombocythemia (ET) include age (≥ 60
years) and previous vascular events. Recently, also leukocytosis has been proposed in risk …

Current opinion in essential thrombocythemia: pathogenesis, diagnosis, and management

A Tefferi, S Murphy - Blood reviews, 2001 - Elsevier
A working diagnosis of essential thrombocythemia (ET) is made in the presence of
nonreactive thrombocytosis and after the exclusion of another chronic myeloid disorder that …

Thrombosis and survival in essential thrombocythemia: a regional study of 1,144 patients

M Montanaro, R Latagliata, M Cedrone… - American journal of …, 2014 - Wiley Online Library
To identify prognostic factors affecting thrombosis‐free survival (TFS) and overall survival
(OS), we report the experience of a Regional cooperative group in a real‐life cohort of 1,144 …

Leukocytosis and risk stratification assessment in essential thrombocythemia

A Carobbio, E Antonioli, P Guglielmelli… - Journal of Clinical …, 2008 - ascopubs.org
Purpose Established risk factors for thrombosis in essential thrombocythemia (ET) include
age and previous vascular events. We aimed to refine this risk stratification by adding …

Leukocytosis is a risk factor for thrombosis in essential thrombocythemia: interaction with treatment, standard risk factors, and Jak2 mutation status

A Carobbio, G Finazzi, V Guerini, O Spinelli, F Delaini… - Blood, 2007 - ashpublications.org
Leukocytes contribute to the pathogenesis of thrombosis in essential thrombocythemia (ET)
through recently discovered mechanisms of activation and interaction with platelets and …

Essential thrombocythemia beyond the first decade: life expectancy, long-term complication rates, and prognostic factors

AP Wolanskyj, SM Schwager, RF McClure… - Mayo Clinic …, 2006 - Elsevier
OBJECTIVE To describe the long-term natural history of essential thrombocythemia (ET) in
terms of life expectancy, risk of disease transformation into a more aggressive myeloid …

Risk factors for arterial and venous thrombosis in WHO-defined essential thrombocythemia: an international study of 891 patients

A Carobbio, J Thiele, F Passamonti… - Blood, The Journal …, 2011 - ashpublications.org
In an international collaborative study, a central histologic review identified 891 patients with
essential thrombocythemia, strictly defined by World Health Organization criteria. After a …