1. The responses to glutamate and amino acid antagonists of cells in the cuneate nucleus of
anaesthetized rats have been examined. 2. 1‐hydroxy‐3‐amino‐pyrrolidone‐2 (HA‐966) …

An investigation was made of the mechanism of depolarization of spinal motoneurones by
excitant amino acids, and of possible antagonists of the excitation of spinal, thalamic and …

1. Pyramidal tract interneurones, defined as neurones which are activated synaptically as a
result of pyramidal tract stimulation, have been identified in the rat cerebral cortex. The …

1. The relative potencies of a number of analogues of L‐glutamate as excitants of thalamic
neurones in the rat have been compared. The most powerful compounds were kainate …

1. Presynaptic inhibition was evoked in the rat cuneate nucleus by a peripheral conditioning
stimulus. The dicarboxylic amino acid salts glutamate and aspartate and the neutral amino …

1. Intracellular recordings were made from rat striatal neurones in vitro. The cells had resting
membrane potentials greater than‐60 mV and action potentials greater than 70 mV with …

Granule cells of the dentate gyrus in the hippocampi of anaesthetized rats were excited by
stimulation of the contralateral hippocampus (the commissural input) and the ipsilateral …

Abstract 1 Glutamate and the excitatory aminoacid antagonist, alpha-aminoadipic acid
(alphaAA), have been applied by microiontophoresis to Purkinje cells in the rat cerebellum …

Firing rates of single thalamic neurones of the cat and the rat have been measured as
functions of the currents used to apply glutamic and aspartic acids electrophoretically. Hill …

Amino acids related to L‐glutamic and γ‐amino‐n‐butyric acid have been administered
electrophoretically, and by pressure ejection, into the extraneuronal environment of single …