An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans
J Wu, J Xi, Z Zhu, Q Peng, C Liu, Z Wan, Y Cao, X Chen… - bioRxiv, 2024 - biorxiv.org
Humans are frequently exposed to a multitude of chemicals daily, necessitating efficient
methods for rapidly assessing toxicity and potential health risks. Microfluidics has shown …
methods for rapidly assessing toxicity and potential health risks. Microfluidics has shown …
[HTML][HTML] Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms
The nematode Caenorhabditis elegans is a suitable model organism in drug screening.
Traditionally worms are grown on agar plates, posing many challenges for long-term culture …
Traditionally worms are grown on agar plates, posing many challenges for long-term culture …
Caenorhabditis elegans-on-a-chip: microfluidic platforms for high-resolution imaging and phenotyping
S Mondal, A Ben-Yakar - Organ-on-a-chip, 2020 - Elsevier
Caenorhabditis elegans is an attractive alternative animal model for identifying toxicological
phenotypes in vivo, studying the mode of action of drugs, and characterizing physiological …
phenotypes in vivo, studying the mode of action of drugs, and characterizing physiological …
[HTML][HTML] A high-throughput microplate toxicity screening platform based on Caenorhabditis elegans
J Wu, Y Gao, J Xi, X You, X Zhang, X Zhang… - Ecotoxicology and …, 2022 - Elsevier
Abstract Caenorhabditis elegans (C. elegans), an established model organism, has been
widely used in environmental toxicology research. However, most of the current toxicity …
widely used in environmental toxicology research. However, most of the current toxicity …
Advances in C. áelegans behavior research with microfluidic devices and its future prospects in the evaluation of exogenous pollutants
The nematode Caenorhabditis elegans (C. áelegans) is characterized by small size, a
transparent body, and a simple structure. However, traditional techniques (eg, sorting and …
transparent body, and a simple structure. However, traditional techniques (eg, sorting and …
[HTML][HTML] Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans
The nematode C. elegans (worm) is a small invertebrate animal widely used in studies
related to fundamental biological processes, disease modelling, and drug discovery. Due to …
related to fundamental biological processes, disease modelling, and drug discovery. Due to …
Microfluidic chamber arrays for whole-organism behavior-based chemical screening
The nematode Caenorhabditis elegans is an important model organism in genetic research
and drug screening because of its relative simplicity, ease of maintenance, amenability to …
and drug screening because of its relative simplicity, ease of maintenance, amenability to …
Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans
M Cornaglia, T Lehnert, MAM Gijs - Lab on a Chip, 2017 - pubs.rsc.org
In a typical high-throughput drug screening (HTS) process, up to millions of chemical
compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit …
compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit …
[HTML][HTML] Microfluidics as a tool for C. elegans research
A San-Miguel, H Lu - WormBook: The Online Review of C. elegans …, 2018 - ncbi.nlm.nih.gov
Microfluidics has emerged as a set of powerful tools that have greatly advanced some areas
of biological research, including research using C. elegans. The use of microfluidics has …
of biological research, including research using C. elegans. The use of microfluidics has …
A microfluidic device for efficient chemical testing using Caenorhabditis elegans
P Song, W Zhang, A Sobolevski, K Bernard… - Biomedical …, 2015 - Springer
The nematode worm Caenorhabditis elegans has been employed as a popular model
organism in many fields of biological research. In this paper, we present a microfluidic …
organism in many fields of biological research. In this paper, we present a microfluidic …