Lymph nodes (LNs) are peripheral lymphoid organs essential for vaccine-induced immune
responses. Although cationic liposomes have been documented as a novel adjuvant and …

Subunit proteins provide a safe source of antigens for vaccine development especially for
intracellular infections which require the induction of strong cellular immune responses …

Although retaining antigens at the injection site (the so-called “depot effect”) is an important
strategy for vaccine development, increasing evidence showed that lymphatic-targeted …

Cationic liposomes are lipid-bilayer vesicles with a positive surface charge that have re-
emerged as a promising new adjuvant technology. Although there is some evidence that …

Purpose Personalized peptide-based cancer vaccines will be composed of multiple patient
specific synthetic long peptides (SLPs) which may have various physicochemical properties …

Cationic liposomes have emerged as a novel adjuvant and antigen delivery system to
enhance vaccine efficacy. However, the role of surface charge density in cationic liposome …

Liposomes not only offer the ability to enhance drug delivery, but can effectively act as
vaccine delivery systems and adjuvants. Their flexibility in size, charge, bilayer rigidity and …

The mechanism behind the immunostimulatory effect of the cationic liposomal vaccine
adjuvant dimethyldioctadecylammonium and trehalose 6, 6′-dibehenate (DDA: TDB) has …

Liposomes (phospholipid bilayer vesicles) are versatile and robust delivery systems for
induction of antibody and T lymphocyte responses to associated subunit antigens. In the last …

In this study we explored the immunization route-dependent adjuvanticity of cationic
liposomes loaded with an antigen (ovalbumin; OVA) and an immune potentiator (CpG). Mice …