[HTML][HTML] The immunopathogenesis of sarcoidosis

J Miedema, F Cinetto, A Smed-Sörensen… - Journal of …, 2024 - Elsevier
Sarcoidosis is a granulomatous multiorgan disease, thought to result from exposure to yet
unidentified antigens in genetically susceptible individuals. The exaggerated inflammatory …

The immunology of sarcoidosis

AK Gerke, G Hunninghake - Clinics in chest medicine, 2008 - Elsevier
Sarcoidosis continues to be a disease of research interest because of its complicated
immune mechanisms and elusive etiology. So far, it has been established that …

Immunologic response of sarcoidosis

G Zissel, A Prasse… - Seminars in respiratory …, 2010 - thieme-connect.com
Sarcoidosis is a chronic granulomatous disorder characterized by an accumulation of T
lymphocytes, macrophages, and immune-effector cells within affected organs. The …

A primer on the clinical aspects of sarcoidosis for the basic and translational scientist

MA Judson - Journal of Clinical Medicine, 2021 - mdpi.com
The immunopathogenesis of sarcoidosis remains unclear. This failure in understanding has
been clinically impactful, as it has impeded the accurate diagnosis, treatment, and …

Sarcoidosis and autoimmunity: In the depth of a complex relationship

L Rizzi, C Sabbà, P Suppressa - Frontiers in Medicine, 2022 - frontiersin.org
Sarcoidosis is a chronic granulomatous disease that can virtually affect any organ. Its
etiology is unknown, although it has been proposed that environmental or biological agents …

[HTML][HTML] Etiology of sarcoidosis: does infection play a role?

S Saidha, ES Sotirchos, C Eckstein - The Yale journal of biology …, 2012 - ncbi.nlm.nih.gov
Sarcoidosis is a granulomatous inflammatory disorder of unclear etiology, which is known to
affect multiple organ systems including the lungs, heart, skin, central nervous system, and …

Etiology of sarcoidosis

ES Chen, DR Moller - Clinics in chest medicine, 2008 - Elsevier
Research over the past decade has advanced our understanding of the pathogenesis of
sarcoidosis and provided new insights into potential causes of this disease. It is important to …

Immunology of sarcoidosis: old companions, new relationships

F Cinetto, R Scarpa, A Dell'Edera… - Current Opinion in …, 2020 - journals.lww.com
Evidence points at microenvironment and cell functional features rather than cell
polarization or differentiation as determinants of pathogenesis. In terms of therapeutic …

Host-microbe interactions in the pathogenesis and clinical course of sarcoidosis

PT Inaoka, M Shono, M Kamada… - Journal of biomedical …, 2019 - Springer
Sarcoidosis is a rare inflammatory disease characterized by the development of granulomas
in various organs, especially in the lungs and lymph nodes. Clinics of the disease largely …

Immunogenetics of disease-causing inflammation in sarcoidosis

J Grunewald, P Spagnolo, J Wahlström… - Clinical reviews in allergy …, 2015 - Springer
Sarcoidosis is a systemic inflammatory disorder characterised by tissue infiltration by
mononuclear phagocytes and lymphocytes with associated non-caseating granuloma …